Carbamic Acid

Carbamic Acid

SCHEMBL4990385

CC(=O)Nc1nc(CCc2ccc(CCNC=NC(=O)O)cc2)cs1.NC(=O)O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 20/20 0.64
MAOB P27338 3/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL3935711 0.94 AOC3 (0.67) AOC3MAOB
Carbamic Acid SCHEMBL3934857 0.92 AOC3 (0.61) AOC3MAOB
SCHEMBL4291906 0.88 AOC3 (0.67) AOC3MAOB
Carbamic Acid SCHEMBL4887529 0.88 AOC3 (0.51) AOC3MAOB
Carbamic Acid SCHEMBL4869434 0.88 AOC3 (0.65) AOC3MAOB
Carbamic Acid SCHEMBL4874668 0.87 AOC3 (0.66) AOC3MAOB
Carbamic Acid SCHEMBL3936159 0.86 AOC3 (0.67) AOC3MAOB
Carbamic Acid SCHEMBL4881050 0.84 AOC3 (0.49) AOC3MAOB
Carbamic Acid SCHEMBL4888141 0.82 AOC3 (0.51) AOC3MAOB
Carbamic Acid SCHEMBL3932678 0.82 AOC3 (0.65) AOC3MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1608365-B1 METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE R TECH UENO LTD (JP) 2013-10-02 EP disclosed
US-20080119462-A1 METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE SUCAMPO AG (CH) 2008-05-22 US disclosed
US-7125901-B2 Thiazole derivatives ASTELLAS PHARMA INC. (JP) 2006-10-24 US disclosed
US-20060128770-A1 Thiazole derivatives FUJISAWA PHARMACEUTICAL CO. LTD. (JP) 2006-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080119462-A1 METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE VCAM1, ICAM1, VAPB AOC3 202/4885MAOB 923/4885
US-20060128770-A1 Thiazole derivatives VCAM1, ICAM1, TXNL1 AOC3 782/4885MAOB 4191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.