Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1765023 | 1.00 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL14862746 | 1.00 | ALDH1A1 (0.33) | ALDH1A1 | |
| Water SCHEMBL9834052 | 0.98 | ALDH1A1 (0.32) | ALDH1A1 | |
| Water SCHEMBL9833095 | 0.98 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL11361884 | 0.98 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL60852 | 0.95 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL7775476 | 0.92 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL27954070 | 0.87 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL11663000 | 0.87 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL5892635 | 0.86 | ALDH1A1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766352-B1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIV HEALTH NETWORK UHN (CA) | 2018-06-06 | — | — | EP | claimed |
| EP-2766352-A1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | University Health Network (UHN) (CA) | 2014-08-20 | — | — | EP | claimed |
| US-20140051679-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERISTY HEALTH NETWORKS (CA) | 2014-02-20 | — | — | US | claimed |
| WO-2013053051-A1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2013-04-18 | — | — | WO | claimed |
| US-5637610-A | ANTICHOLESTEROL AGENT | SUNTORY LIMITED (JP) | 1997-06-10 | — | — | US | claimed |
| US-5270335-A | Administering a dioxabicyclo(3.3.0)octane | SUNTORY LIMITED (JP) | 1993-12-14 | — | — | US | claimed |
| US-4684740-A | Production of 2,6-bis (4-hydroxy-3,5-dimethoxyphenyl-3,7-dioxabicyclo (3.3.0) octane | JUJO PAPER CO., LTD. (JP) | 1987-08-04 | — | — | US | claimed |
| CN-114410604-B | Epoxide hydrolase and encoding gene and application thereof | 浙江大学 | 2023-11-14 | — | — | CN | disclosed |
| US-11466044-B2 | Neomycin and paromomycin derivatives | WAYNE STATE UNIVERSITY (US) | 2022-10-11 | — | — | US | disclosed |
| US-20210107932-A1 | NEOMYCIN AND PAROMOMYCIN DERIVATIVES | WAYNE STATE UNIVERSITY (US) | 2021-04-15 | — | — | US | disclosed |
| US-10364196-B2 | Multi-functional coating system for cementitious composite materials | James Hardie Technology Limited (IE) | 2019-07-30 | — | — | US | disclosed |
| WO-2018187738-A1 | NEOMYCIN AND PAROMOMYCIN DERIVATIVES | WAYNE STATE UNIVERSITY (US) | 2018-10-11 | — | — | WO | disclosed |
| EP-2766352-B1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIV HEALTH NETWORK UHN (CA) | 2018-06-06 | — | — | EP | disclosed |
| EP-0302599-A2 | Bicyclo-octane and bicyclo-nonane derivatives, processes for their preparation and their use as herbicides | HER MAJESTY THE QUEEN IN RIGHT OF NEW ZEALAND, DEPARTMENT OF SCIENTIFIC AND INDUSTRIAL RESEARCH, CHEMISTRY DIVISON (NZ) | 1989-02-08 | — | — | EP | disclosed |
| EP-0046679-A2 | Total synthesis of 1RS,4SR,5RS-4-(4,8-dimethyl-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo(3.2.1)octane-1-acetic acid | ORTHO PHARMACEUTICAL CORPORATION (US) | 1982-03-03 | — | — | EP | disclosed |
| US-4307019-A | Total synthesis of 1RS,4SR,5RS,-4-(4,8-dimethyl-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid | ORTHO PHARMACEUTICAL CORPORATION (US) | 1981-12-22 | — | — | US | disclosed |
| US-4277401-A | MANY STEPS STARTING FROM 1-BROMO-6-METHYL-2-OXO-5-NONEN-9-OIC ACID | ORTHO PHARMACEUTICAL CORPORATION (US) | 1981-07-07 | — | — | US | disclosed |
| US-4101527-A | Moisture curing polymers prepared from polyfunctional isocyanates and a dioxazabicyclo octane | THE SHERWIN-WILLIAMS COMPANY (US) | 1978-07-18 | — | — | US | disclosed |
| US-4058607-A | DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES | AIRWICK INDUSTRIES, INC. (US) | 1977-11-15 | — | — | US | disclosed |
| US-3962415-A | Insecticide evaporator comprising DDVP with synergized benzodioxole compound as stabilizer | AIRWICK INDUSTRIES, INC. (US) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11466044-B2 | Neomycin and paromomycin derivatives | NEK9, NEK5, NEK1 | ALDH1A1 4659/4885 |
| US-20140051679-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | MAP3K7, MAP3K1, MAP3K20 | ALDH1A1 2710/4885 |
| US-20210107932-A1 | NEOMYCIN AND PAROMOMYCIN DERIVATIVES | NEK9, NEK5, NEK1 | ALDH1A1 4659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.