Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK3 | P49761 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5003086 | 0.84 | CYP11B1 (0.47) | CYP11B1CYP11B2AXLCLK2CLK3 | |
| SCHEMBL4992325 | 0.82 | MEN1 (0.43) | CYP11B1CYP11B2MAPTHTTMEN1 | |
| SCHEMBL4997662 | 0.82 | CYP11B1 (0.46) | CYP11B1CYP11B2MAPTAXLLMNA | |
| SCHEMBL5000820 | 0.81 | PIM1 (0.48) | CYP11B1CYP11B2MAPTHTTMEN1 | |
| SCHEMBL4995444 | 0.80 | SMN1; SMN2 (0.50) | MAPTHTTMAPK1MEN1KMT2A | |
| SCHEMBL5003151 | 0.79 | MAPT (0.50) | CYP11B1CYP11B2MAPTMAPK1MEN1 | |
| SCHEMBL4992156 | 0.79 | CYP11B1 (0.49) | CYP11B1CYP11B2CLK2CLK3DYRK1A | |
| SCHEMBL4995171 | 0.78 | MEN1 (0.42) | CYP11B1CYP11B2MAPTHTTMEN1 | |
| SCHEMBL5003013 | 0.78 | CYP11B2 (0.60) | CYP11B1CYP11B2MAPTHTTLMNA | |
| SCHEMBL5000719 | 0.77 | CYP11B1 (0.47) | CYP11B1CYP11B2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194574-A1 | Pyrazine Derivatives As Effective Compounds Against Infectious Diseases | AXXIMA PHARMACEUTICALS AG (DE) | 2008-08-14 | — | — | US | claimed |
| US-7423110-B2 | Polysulfone compositions exhibiting very low color and high light transmittance properties and articles made therefrom | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2008-09-09 | — | — | US | disclosed |
| US-20050176923-A1 | Polysulfone compositions exhibiting very low color and high light transmittance properties and articles made therefrom | SOLVAY ADVANCED POLYMERS, LLC (US) | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194574-A1 | Pyrazine Derivatives As Effective Compounds Against Infectious Diseases | PRNP, PSEN1, PPP5C | CYP11B1 132/4885CYP11B2 112/4885MAPT 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.