Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.79 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13840738 | 0.89 | ADRB2 (0.74) | ADRB2CHRM3ADRB1 | |
| SCHEMBL3915477 | 0.89 | ADRB2 (0.74) | ADRB2CHRM3ADRB1 | |
| SCHEMBL3625837 | 0.88 | ADRB2 (0.81) | ADRB2CHRM3 | |
| Pf-00610355 SCHEMBL29369227 | 0.88 | ADRB2 (1.00) | ADRB2CHRM3 | |
| Pf-00610355 SCHEMBL2452494 | 0.88 | ADRB2 (1.00) | ADRB2CHRM3 | |
| SCHEMBL3625842 | 0.88 | ADRB2 (0.81) | ADRB2CHRM3 | |
| Pf-00610355 SCHEMBL2452493 | 0.88 | ADRB2 (1.00) | ADRB2CHRM3 | |
| Methane SCHEMBL15936063 | 0.87 | ADRB2 (0.72) | ADRB2CHRM3ADRB1 | |
| SCHEMBL4856625 | 0.85 | ADRB2 (0.68) | ADRB2CHRM3ADRB1 | |
| SCHEMBL4856636 | 0.85 | ADRB2 (0.68) | ADRB2CHRM3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080193988-A1 | Such as 2-(3-{2-[((2R)-2-{4-Benzyloxy-3-[(dimethylsulfonyl)amino]phenyl}-2-{[tert-butyl(dimethyl)silyl]oxy}ethyl)amino]-2-methylpropyl}phenyl)-N-[(4'-hydroxybiphenyl-3-yl)methyl]-acetamide | GLADWELL IAIN ROBERT | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080193988-A1 | Such as 2-(3-{2-[((2R)-2-{4-Benzyloxy-3-[(dimethylsulfonyl)amino]phenyl}-2-{[tert-butyl(dimethyl)silyl]oxy}ethyl)amino]-2-methylpropyl}phenyl)-N-[(4'-hydroxybiphenyl-3-yl)methyl]-acetamide | NR4A1, CYP2A6, GPR6 | ADRB2 118/4885CHRM3 257/4885ADRB1 266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.