Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.51 |
| ▸ | DNMT3A | Q9Y6K1 | 2/20 | 0.51 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5409621 | 0.78 | MAOB (0.60) | NPC1RAB9AJAK2MAOBDYRK3 | |
| SCHEMBL5417481 | 0.77 | NPC1 (0.60) | NPC1RAB9AJAK2MAOBMEN1 | |
| SCHEMBL5412611 | 0.77 | NPC1 (0.63) | NPC1RAB9AJAK2MAOBMEN1 | |
| SCHEMBL5415057 | 0.77 | RAB9A (0.58) | NPC1RAB9AJAK2MAOBCYP1A2 | |
| SCHEMBL5182382 | 0.76 | NPC1 (0.75) | NPC1RAB9AJAK2MAOBDYRK3 | |
| SCHEMBL5417950 | 0.76 | NPC1 (0.56) | NPC1RAB9AJAK2MAOBDYRK3 | |
| SCHEMBL5425600 | 0.75 | NPC1 (0.64) | NPC1RAB9AMAOBMEN1KMT2A | |
| SCHEMBL5412584 | 0.74 | MAOB (0.64) | NPC1RAB9AJAK2MAOBMEN1 | |
| SCHEMBL5415117 | 0.73 | MAOB (0.80) | NPC1RAB9AJAK2MAOBL3MBTL1 | |
| SCHEMBL9959880 | 0.73 | MAOB (0.63) | NPC1RAB9AJAK2MAOBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080153810-A1 | INDAZOLE DERIVATIVES USEFUL AS MELANIN CONCENTRATING RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-06-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153810-A1 | INDAZOLE DERIVATIVES USEFUL AS MELANIN CONCENTRATING RECEPTOR LIGANDS | MCHR1, MCHR2, MC1R | NPC1 168/4885RAB9A 1460/4885JAK2 337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.