Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4998920 | 0.87 | P2RX7 (0.67) | P2RX7P2RX3 | |
| SCHEMBL4147713 | 0.83 | P2RX7 (0.76) | P2RX7P2RX3 | |
| SCHEMBL4140388 | 0.83 | P2RX7 (0.76) | P2RX7P2RX3 | |
| SCHEMBL4155089 | 0.83 | P2RX7 (0.76) | P2RX7P2RX3 | |
| SCHEMBL4139538 | 0.82 | P2RX7 (0.73) | P2RX7P2RX3 | |
| SCHEMBL4150463 | 0.81 | P2RX7 (0.70) | P2RX7P2RX3 | |
| SCHEMBL4132829 | 0.81 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL13243972 | 0.81 | P2RX7 (0.79) | P2RX7P2RX3 | |
| SCHEMBL4995575 | 0.81 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL3001567 | 0.81 | P2RX7 (1.00) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402596-B2 | Bicycloheteroaryl compounds as P2X7 modulators and uses thereof | RENOVIS, INC. (US) | 2008-07-22 | — | — | US | claimed |