Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4986631 | 0.95 | FOLH1 (0.38) | C3AR1ALDH1A1POLBBRD4ALOX12 | |
| SCHEMBL14090894 | 0.94 | ALDH1A1 (0.35) | ALDH1A1POLBBRD4ALOX12SIRT2 | |
| SCHEMBL14090913 | 0.86 | NPSR1 (0.41) | ALDH1A1POLBKDM4E | |
| SCHEMBL4430961 | 0.85 | C3AR1 (0.37) | C3AR1ALDH1A1BRD4ITGB1ITGA4 | |
| SCHEMBL14090798 | 0.81 | C3AR1 (0.35) | C3AR1ALDH1A1POLBBRD4ITGB1 | |
| SCHEMBL4553810 | 0.81 | C3AR1 (0.39) | C3AR1ALDH1A1POLBBRD4MMP8 | |
| SCHEMBL14115149 | 0.81 | C3AR1 (0.35) | C3AR1ALDH1A1POLBBRD4ITGB1 | |
| SCHEMBL4553808 | 0.81 | C3AR1 (0.39) | C3AR1ALDH1A1POLBBRD4MMP8 | |
| SCHEMBL14115720 | 0.81 | C3AR1 (0.35) | C3AR1ALDH1A1POLBBRD4ITGB1 | |
| SCHEMBL4987802 | 0.81 | NPSR1 (0.40) | C3AR1ALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | ENCYSIVE PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | C3AR1, C5, C5AR1 | C3AR1 1/4885ALDH1A1 1639/4885POLB 4248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.