SCHEMBL499439

SCHEMBL499439

O=C(O)c1ccc2c(C(=O)O)ccc(C(=O)O)c2c1C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.56
TYMS P04818 1/20 0.43
NR4A1 P22736 1/20 0.39
NR4A2 P43354 1/20 0.39
NR4A3 Q92570 1/20 0.39
ALDH1A1 P00352 3/20 0.39
ALOX15 P16050 1/20 0.39
KDM4E B2RXH2 3/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
HSD17B10 Q99714 2/20 0.38
POLB P06746 2/20 0.38
RECQL P46063 2/20 0.38
CASP6 P55212 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
APOBEC3A P31941 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
PTPN1 P18031 1/20 0.37
ACE2 Q9BYF1 2/20 0.37
SELL P14151 1/20 0.37
SELP P16109 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30047473 1.00 CYP1A2 (0.56) CYP1A2TYMSNR4A1NR4A2NR4A3
SCHEMBL9565161 0.84 CYP1A2 (0.67) CYP1A2TYMSNR4A1NR4A2NR4A3
SCHEMBL48997 0.80 CYP1A2 (0.52) CYP1A2NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL29420737 0.80 CYP1A2 (0.52) CYP1A2NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL471822 0.80 CYP1A2 (0.48) CYP1A2TYMSNR4A1NR4A2NR4A3
SCHEMBL29001029 0.78 CYP1A2 (0.52) CYP1A2TYMSNR4A1NR4A2NR4A3
SCHEMBL19177352 0.78 WDR5 (0.47) CYP1A2TYMSNR4A1NR4A2NR4A3
SCHEMBL5549583 0.78 CYP1A2 (0.50) CYP1A2NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL202564 0.78 CYP1A2 (0.50) CYP1A2NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL2302245 0.77 CYP1A2 (0.64) CYP1A2TYMSNR4A1NR4A2NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 505 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210353665-A1 Polymer Hydrogels and Methods of Preparation Thereof GELESIS LLC (US) 2021-11-18 US claimed
US-20210179800-A1 DISPENSABLE POLYIMIDE AEROGEL PREPOLYMER, METHOD OF MAKING THE SAME, METHOD OF USING THE SAME, AND SUBSTRATE COMPRISING PATTERNED POLYIMIDE AEROGEL RAYTHEON COMPANY 2021-06-17 US claimed
WO-2021118671-A1 DISPENSABLE POLYIMIDE AEROGEL PREPOLYMER, METHOD OF MAKING THE SAME, METHOD OF USING THE SAME, AND SUBSTRATE COMPRISING PATTERNED POLYIMIDE AEROGEL RAYTHEON COMPANY (US) 2021-06-17 WO claimed
EP-2178922-B1 POLYMER HYDROGELS AND METHODS OF PREPARATION THEREOF GELESIS LLC (US) 2015-10-07 EP claimed
EP-2463308-B1 Polymer hydrogels and medical use thereof GELESIS LLC (US) 2014-12-03 EP claimed
EP-2463308-A1 Polymer Hydrogels and Medical Use Thereof Sannino, Alessandro (IT) 2012-06-13 EP claimed
US-20100234233-A1 POLYMER HYDROGELS AND METHODS OF PREPARATION THEREOF GELESIS, LLC 2010-09-16 US claimed
US-7691556-B2 Antireflective compositions for photoresists AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-04-06 US claimed
US-7018776-B2 Stable non-photosensitive polyimide precursor compositions for use in bilayer imaging systems ARCH SPECIALTY CHEMICALS, INC. (US) 2006-03-28 US claimed
US-20040161711-A1 Stable non-photosensitive polyimide precursor compositions for use in bilayer imaging systems ARCH SPECIALTY CHEMICALS, INC. 2004-08-19 US claimed
US-20040161619-A1 Process for producing a heat resistant relief structure ARCH SPECIALTY CHEMICALS, INC. 2004-08-19 US claimed
US-4510236-A 2-(HYDROXYMETHYL)-1(2H)-PHTHALAZINONE AS TONER PRECURSOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-04-09 US claimed
US-20250189895-A1 METHOD OF MANUFACTURING PLATED ARTICLE TOKYO OHKA KOGYO CO., LTD. (JP) 2025-06-12 US disclosed
US-20250172872-A1 CHEMICALLY AMPLIFIED POSITIVE-TYPE PHOTOSENSITIVE COMPOSITION, METHOD OF MANUFACTURING SUBSTRATE WITH TEMPLATE, AND METHOD OF MANUFACTURING PLATED ARTICLE TOKYO OHKA KOGYO CO., LTD. (JP) 2025-05-29 US disclosed
US-20250073288-A1 Compositions and Methods for Modulating the Intestinal Microbiome GELESIS, LLC 2025-03-06 US disclosed
EP-3961676-B1 ETCHING METHOD AND PHOTOSENSITIVE RESIN COMPOSITION TOKYO OHKA KOGYO CO LTD (JP) 2025-01-22 EP disclosed
EP-0242891-A2 Sheet moulding compound and an upper layer for it DSM RESINS B.V. (NL) 1987-10-28 EP disclosed
US-4487894-A REACTING POLYEPOXIDES WITH POLYIMIDE DIANHYDRIDE AND POLYIMIDE DIAMINE PLASTICS ENGINEERING COMPANY (US) 1984-12-11 US disclosed
US-4421905-A METAL ACETYLACETONATE AS POLYMERIZATION CATALYSTS PLASTICS ENGINEERING COMPANY (US) 1983-12-20 US disclosed
US-4410664-A POLYIMIDE DIANHYDRIDE, POLYEPOXIDE, POLYIMIDE DIAMINE PLASTICS ENGINEERING COMPANY (US) 1983-10-18 US disclosed