Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 2/20 | 0.49 |
| ▸ | ALB | P02768 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.43 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.43 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.43 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14090780 | 1.00 | C3AR1 (0.49) | C3AR1ALBPTPN1FOLH1CA2 | |
| SCHEMBL7925397 | 0.90 | C3AR1 (0.52) | C3AR1ALBFOLH1CA2CA1 | |
| SCHEMBL188589 | 0.90 | C3AR1 (0.52) | C3AR1ALBFOLH1CA2CA1 | |
| SCHEMBL188590 | 0.90 | C3AR1 (0.52) | C3AR1ALBFOLH1CA2CA1 | |
| SCHEMBL4987830 | 0.90 | PRSS1 (0.48) | C3AR1F10GRIN1GRIN2APADI6 | |
| SCHEMBL14090765 | 0.90 | PRSS1 (0.48) | C3AR1F10GRIN1GRIN2APADI6 | |
| SCHEMBL17104389 | 0.88 | TPSAB1 (0.47) | C3AR1ALBFOLH1CA2CA1 | |
| SCHEMBL17104397 | 0.88 | FOLH1 (0.47) | C3AR1ALBFOLH1CA2CA1 | |
| SCHEMBL17104379 | 0.88 | FOLH1 (0.47) | C3AR1ALBFOLH1CA2CA1 | |
| SCHEMBL17104386 | 0.88 | TPSAB1 (0.47) | C3AR1ALBFOLH1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | ENCYSIVE PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | ENCYSIVE PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | ENCYSIVE PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | C3AR1, C5, C5AR1 | C3AR1 1/4885ALB 1064/4885PTPN1 1471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.