Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CCR1 | P32246 | 3/20 | 0.50 |
| ▸ | CCR5 | P51681 | 3/20 | 0.50 |
| ▸ | CCR8 | P51685 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30031 | 0.94 | KDM4E (0.56) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL3924522 | 0.92 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL16241838 | 0.92 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| Hydrochloric Acid SCHEMBL932365 | 0.92 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL16241819 | 0.92 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL78140 | 0.92 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL933820 | 0.92 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL15436287 | 0.92 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL1652383 | 0.92 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL319436 | 0.92 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12006334-B2 | Alkynylplatinum (II) terpyridine system coupled with rhodamine derivative: interplay of aggregation, de-aggregation and ring-opening processes for ratiometric luminescence sensing | SOUTH UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA (CN) | 2024-06-11 | — | — | US | disclosed |
| US-20210002312-A1 | ALKYNYLPLATINUM (II) TERPYRIDINE SYSTEM COUPLED WITH RHODAMINE DERIVATIVE: INTERPLAY OF AGGREGATION, DE-AGGREGATION AND RING-OPENING PROCESSES FOR RATIOMETRIC LUMINESCENCE SENSING | SOUTH UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA (CN) | 2021-01-07 | — | — | US | disclosed |
| US-8309304-B2 | composition for detecting and/or characterizing a multiple-charged biomolecule comprising a charged d8 or d10 metal complex, wherein the metal complex electrostatically binds to the multiple-charged biomolecule to induce aggregation and self-assembly of the metal complex through metal-metal interactions, | THE UNIVERSITY OF HONG KONG (CN) | 2012-11-13 | — | — | US | disclosed |
| US-20080153103-A1 | Label-Free Optical Sensing and Characterization of Biomolecules by D8 or D10 Metal Complexes | UNIVERSITY OF HONG KONG, THE (HK) | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210002312-A1 | ALKYNYLPLATINUM (II) TERPYRIDINE SYSTEM COUPLED WITH RHODAMINE DERIVATIVE: INTERPLAY OF AGGREGATION, DE-AGGREGATION AND RING-OPENING PROCESSES FOR RATIOMETRIC LUMINESCENCE SENSING | TRRAP, TARDBP, TPR | KDM4E 4083/4885LMNA 2866/4885CCR1 4740/4885 |
| US-12006334-B2 | Alkynylplatinum (II) terpyridine system coupled with rhodamine derivative: interplay of aggregation, de-aggregation and ring-opening processes for ratiometric luminescence sensing | TRRAP, TARDBP, TPR | KDM4E 4083/4885LMNA 2866/4885CCR1 4740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.