⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960686 | 0.63 | — | — | |
| SCHEMBL29027394 | 0.60 | — | — | |
| SCHEMBL1797068 | 0.60 | — | — | |
| SCHEMBL8104042 | 0.58 | — | — | |
| SCHEMBL3149716 | 0.58 | — | — | |
| SCHEMBL218489 | 0.56 | — | — | |
| SCHEMBL7647878 | 0.56 | — | — | |
| SCHEMBL1177685 | 0.56 | HSD17B10 (0.32) | — | |
| SCHEMBL1091555 | 0.56 | — | — | |
| SCHEMBL1768522 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417053-B2 | Pyrazolo[1,5-a]pyridine derivatives or pharmaceutically acceptable salts thereof | TEIJIN PHARMA LIMITED (JP) | 2008-08-26 | — | — | US | disclosed |
| EP-1873154-A1 | PYRAZOLO[1,5-a]PYRIDINE DERIVATIVE OR MEDICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2008-01-02 | — | — | EP | disclosed |
| US-20070072898-A1 | Pyrazolo[1,5-a]pyridine derivatives or pharmaceutically acceptable salts thereof | TEIJIN PHARMA LIMITED | 2007-03-29 | — | — | US | disclosed |