Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 13/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4995119 | 0.81 | P2RX7 (0.45) | P2RX7 | |
| SCHEMBL4142225 | 0.80 | P2RX7 (0.51) | P2RX7 | |
| SCHEMBL13243891 | 0.80 | P2RX7 (0.58) | P2RX7 | |
| SCHEMBL13243892 | 0.80 | P2RX7 (0.58) | P2RX7 | |
| SCHEMBL4132901 | 0.80 | P2RX7 (0.57) | P2RX7 | |
| SCHEMBL4994112 | 0.79 | P2RX7 (0.66) | P2RX7 | |
| SCHEMBL23867068 | 0.78 | P2RX7 (0.60) | P2RX7 | |
| SCHEMBL4999038 | 0.77 | P2RX7 (0.46) | P2RX7 | |
| SCHEMBL4984968 | 0.76 | P2RX7 (0.45) | P2RX7 | |
| SCHEMBL4135931 | 0.75 | P2RX7 (0.46) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402596-B2 | Bicycloheteroaryl compounds as P2X7 modulators and uses thereof | RENOVIS, INC. (US) | 2008-07-22 | — | — | US | claimed |