⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19955089 | 1.00 | — | — | |
| SCHEMBL15145775 | 1.00 | — | — | |
| SCHEMBL28463617 | 0.97 | ALDH1A1 (0.35) | — | |
| SCHEMBL19093851 | 0.97 | — | — | |
| SCHEMBL10776897 | 0.97 | ALDH1A1 (0.35) | — | |
| SCHEMBL2669520 | 0.92 | — | — | |
| SCHEMBL37484 | 0.92 | — | — | |
| SCHEMBL12712 | 0.92 | — | — | |
| SCHEMBL16779785 | 0.90 | ALDH1A1 (0.40) | — | |
| Tetrahydrofuran SCHEMBL7096633 | 0.86 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106221-B2 | Renin inhibitors | VITAE PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | claimed |
| US-20100144825-A1 | Renin Inhibitors | VITAE PHARMACEUTICALS, INC. | 2010-06-10 | — | — | US | claimed |
| WO-2008156816-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | claimed |
| CN-107408734-B | Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery using same | 三菱化学株式会社 | 2020-08-18 | — | — | CN | disclosed |
| EP-3273520-B1 | NONAQUEOUS ELECTROLYTE AND NONAQUEOUS ELECTROLYTE SECONDARY CELL IN WHICH SAME IS USED | MITSUBISHI CHEM CORP (JP) | 2020-05-06 | — | — | EP | disclosed |
| US-10604717-B2 | Lubricant composition for an engine | TOTAL MARKETING SERVICES (FR) | 2020-03-31 | — | — | US | disclosed |
| US-10424812-B2 | Non-aqueous electrolytic solution and non-aqueous electrolyte secondary battery using the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2019-09-24 | — | — | US | disclosed |
| US-10424813-B2 | Non-aqueous electrolyte solution and non-aqueous electrolyte secondary battery using same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2019-09-24 | — | — | US | disclosed |
| EP-2978827-B1 | OIL SOLUBLE POLYOXYBUTYLENE POLYMERS AS FRICTION MODIFIERS FOR LUBRICANTS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-08-14 | — | — | EP | disclosed |
| CN-107116869-B | Multilayer structure making, pneumatic tire inner liner and pneumatic tire | 株式会社普利司通 | 2019-04-30 | — | — | CN | disclosed |
| CN-109661428-A | Resin combination and application thereof | 株式会社可乐丽 | 2019-04-19 | — | — | CN | disclosed |
| EP-1391470-B1 | Process for preparing polymer compound for resist | GUN EI CHEMICAL INDUSTRY CO LTD (JP) | 2007-10-31 | — | — | EP | disclosed |
| US-7268134-B2 | Medical devices employing triazine compounds and compositions thereof | REDDY US THERAPEUTICS, INC. (US) | 2007-09-11 | — | — | US | disclosed |
| US-7268134-B2 | Medical devices employing triazine compounds and compositions thereof | REDDY US THERAPEUTICS, INC. (US) | 2007-09-11 | — | — | US | disclosed |
| US-7265114-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2007-09-04 | — | — | US | disclosed |
| US-7265114-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2007-09-04 | — | — | US | disclosed |
| US-7235560-B2 | Pyrimidine derivative as selective COX-2 inhibitors | GLAXO GROUP LIMITED (GB) | 2007-06-26 | — | — | US | disclosed |
| US-20070142411-A1 | Use of cyclooxygenase-2 selective inhibitors for the treatment of schizophrenic disorders | GLAXO GROUP LIMITED (GB) | 2007-06-21 | — | — | US | disclosed |
| US-4430131-A | Polyurethane binders | HER MAJESTY THE QUEEN IN RIGHT OF CANADA (CA) | 1984-02-07 | — | — | US | disclosed |
| US-4415728-A | BINDERS FOR SOLID PROPELLANTS | HER MAJESTY THE QUEEN IN RIGHT OF CANADA (CA) | 1983-11-15 | — | — | US | disclosed |