(Chloromethyl)Benzene

(Chloromethyl)Benzene

SCHEMBL4998967

CC(C)=C(CCN)C(=O)O.ClCc1ccccc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
ALPI P09923 1/20 0.37
PKM P14618 1/20 0.37
PTGS1 P23219 1/20 0.37
XIAP P98170 1/20 0.37
SLC7A5 Q01650 1/20 0.37
KEAP1 Q14145 1/20 0.36
LMNA P02545 2/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
TSHR P16473 2/20 0.36
SLC15A1 P46059 1/20 0.36
MMP2 P08253 1/20 0.36
CYP2A6 P11509 1/20 0.35
HTR2A P28223 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
LOXL2 Q9Y4K0 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
IDO1 P14902 1/20 0.35
CES2 O00748 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Chloromethyl)Benzene SCHEMBL6442622 0.83 ALDH1A1 (0.39) ALDH1A1ALPIPKMPTGS1XIAP
Chloromethane SCHEMBL203881 0.80 GRIK1 (0.43) ALDH1A1LMNATSHRHDAC3HDAC4
SCHEMBL724564 0.80 GRIK1 (0.46) ALDH1A1LMNATSHRHDAC3HDAC4
(Chloromethyl)Benzene SCHEMBL27959241 0.78 ALDH1A1 (0.48) ALDH1A1ALPIPKMPTGS1XIAP
(Chloromethyl)Benzene SCHEMBL27525410 0.78 ALDH1A1 (0.48) ALDH1A1ALPIPKMPTGS1XIAP
(Chloromethyl)Benzene SCHEMBL27410445 0.78 ALDH1A1 (0.52) ALDH1A1ALPIPKMPTGS1XIAP
(Chloromethyl)Benzene SCHEMBL27562557 0.78 ALDH1A1 (0.52) ALDH1A1ALPIPKMPTGS1XIAP
SCHEMBL21598322 0.77 ALDH1A1 (0.64) ALDH1A1KEAP1SMN1; SMN2NPC1RAB9A
(Chloromethyl)Benzene SCHEMBL18894568 0.74 ALDH1A1 (0.45) ALDH1A1ALPIPKMPTGS1XIAP
(Chloromethyl)Benzene SCHEMBL15574672 0.74 CYP2C9 (0.42) ALDH1A1ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7442280-B1 Process for the production of paper AKZO NOBEL NV (NL) 2008-10-28 US claimed
EP-1470292-B1 PROCESS FOR MANUFACTURING PAPER AKZO NOBEL NV (NL) 2014-06-25 EP disclosed