SCHEMBL5000804

SCHEMBL5000804

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nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PGD P52209 3/20 0.61
MPI P34949 1/20 0.61
PGK1 P00558 1/20 0.54
PGK2 P07205 1/20 0.54
LPAR5 Q9H1C0 1/20 0.40
SGPL1 O95470 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16416132 1.00 PGD (0.61) PGDMPIPGK1PGK2LPAR5
SCHEMBL428503 0.91 PGD (0.53) PGDMPIPGK1PGK2
SCHEMBL3515615 0.91 PGD (0.53) PGDMPIPGK1PGK2
SCHEMBL3748606 0.91 PGD (0.53) PGDMPIPGK1PGK2
SCHEMBL1403636 0.91 PGD (0.53) PGDMPIPGK1PGK2
SCHEMBL939456 0.91 PGD (0.53) PGDMPIPGK1PGK2
SCHEMBL17285 0.91 PGD (0.53) PGDMPIPGK1PGK2
SCHEMBL1533840 0.91 PGD (0.53) PGDMPIPGK1PGK2
SCHEMBL20817087 0.91 PGD (0.53) PGDMPIPGK1PGK2
SCHEMBL18341413 0.89 PGD (0.67) PGDMPIPGK1PGK2LPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 US disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-10877035-B2 Advanced drug development and manufacturing ICAGEN, LLC (US) 2020-12-29 US disclosed
US-20200278346-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ADJACENT ACQUISITION CO., LLC 2020-09-03 US disclosed
WO-2018204764-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION (US) 2018-11-08 WO disclosed
US-20150309021-A1 Advanced Drug Development and Manufacturing LOS ALAMOS NATIONAL SECURITY, LLC 2015-10-29 US disclosed
EP-2511844-B1 X-ray microscope XRPRO SCIENCES INC (US) 2015-08-12 EP disclosed
EP-2511844-A2 Advanced drug development and manufacturing Los Alamos National Security, LLC (US) 2012-10-17 EP disclosed
EP-2084519-B1 X-RAY FLUORESCENCE ANALYSIS METHOD LOS ALAMOS NAT SECURITY LLC (US) 2012-08-01 EP disclosed
US-20080220441-A1 Advanced drug development and manufacturing THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2008-09-11 US disclosed