Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | KDM1A | O60341 | 5/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.50 |
| ▸ | HTR1A | P08908 | 4/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.50 |
| ▸ | DRD1 | P21728 | 4/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.50 |
| ▸ | DRD3 | P35462 | 4/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019998 | 0.85 | CYP2D6 (0.67) | CYP2D6CYP2C19CYP3A4KDM1APTGS1 | |
| SCHEMBL29422798 | 0.83 | CYP3A4 (0.43) | CYP2D6CYP2C19CYP3A4KDM1APTGS1 | |
| SCHEMBL564939 | 0.83 | CYP3A4 (0.43) | CYP2D6CYP2C19CYP3A4KDM1APTGS1 | |
| SCHEMBL18550493 | 0.80 | CYP2D6 (0.56) | CYP2D6CYP2C19CYP3A4KDM1APTGS1 | |
| SCHEMBL29557425 | 0.77 | KDM1A (0.61) | CYP2D6CYP2C19CYP3A4KDM1APTGS1 | |
| SCHEMBL293951 | 0.77 | KDM1A (0.61) | CYP2D6CYP2C19CYP3A4KDM1APTGS1 | |
| SCHEMBL790773 | 0.74 | CYP2D6 (0.57) | CYP2D6CYP2C19CYP3A4KDM1APTGS1 | |
| SCHEMBL6494892 | 0.74 | CYP2D6 (0.50) | CYP2D6CYP2C19CYP3A4KDM1APTGS1 | |
| SCHEMBL12933361 | 0.74 | TSHR (0.56) | CYP2D6CYP2C19CYP3A4CHRM1LMNA | |
| SCHEMBL12691840 | 0.74 | CYP3A4 (0.37) | CYP2D6CYP2C19CYP3A4ALDH1A1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812822-B1 | ELECTROCHROMIC MEDIA AND DEVICES | GENTEX CORP (US) | 2019-05-01 | — | — | EP | disclosed |
| CN-101069124-B | Electrochromic compounds and related media and devices | GENTEX CORP | 2013-10-16 | — | — | CN | disclosed |
| US-7428091-B2 | Electrochromic compounds and associated media and devices | GENTEX CORPORATION (US) | 2008-09-23 | — | — | US | disclosed |
| CN-101069124-A | Electrochromic compounds and related media and devices | GENTEX CORP (US) | 2007-11-07 | — | — | CN | disclosed |
| US-20060103911-A1 | Electrochromic compounds and associated media and devices | GENTEX CORPORATION | 2006-05-18 | — | — | US | disclosed |