Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.39 |
| ▸ | PRNP | P04156 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5000805 | 0.74 | CYP2D6 (0.65) | CYP2D6CYP2C19CYP3A4BCHEKDM1A | |
| SCHEMBL8019998 | 0.69 | CYP2D6 (0.67) | CYP2D6CYP2C19CYP3A4BCHEKDM1A | |
| SCHEMBL28222171 | 0.69 | CYP2D6 (0.54) | CYP2D6CYP2C19CYP3A4BCHEKDM1A | |
| SCHEMBL18550493 | 0.68 | CYP2D6 (0.56) | CYP2D6CYP2C19CYP3A4KDM1APTGS1 | |
| SCHEMBL629136 | 0.68 | KDM1A (0.53) | CYP2D6CYP2C19CYP3A4BCHEKDM1A | |
| SCHEMBL10052731 | 0.66 | KDM1A (0.64) | CYP2D6CYP2C19CYP3A4KDM1ALMNA | |
| SCHEMBL10076450 | 0.66 | PTGS1 (0.65) | CYP2D6CYP2C19CYP3A4BCHEKDM1A | |
| SCHEMBL30622707 | 0.65 | KDM1A (0.59) | CYP2D6CYP2C19BCHEKDM1APTGS1 | |
| SCHEMBL18550498 | 0.65 | KDM1A (0.59) | CYP2D6CYP2C19BCHEKDM1APTGS1 | |
| SCHEMBL29557425 | 0.65 | KDM1A (0.61) | CYP2D6CYP2C19CYP3A4BCHEKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080076-A1 | N-desmethyl levomepromazine | XANODYNE PHARMACAL, INC. (US) | 2005-04-14 | — | — | US | disclosed |