Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.75 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.75 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281914 | 1.00 | SLC6A3 (0.75) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7281917 | 1.00 | SLC6A3 (0.75) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9129528 | 1.00 | SLC6A3 (0.75) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7281762 | 1.00 | SLC6A3 (0.75) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7281769 | 1.00 | SLC6A3 (0.75) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL5000854 | 1.00 | SLC6A3 (0.75) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL8694109 | 1.00 | SLC6A3 (0.75) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7089372 | 1.00 | SLC6A3 (0.75) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7088777 | 0.90 | SLC6A3 (0.77) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL5007318 | 0.88 | SLC6A3 (0.73) | SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114487184-B | Method for determining 2 beta-methyl ester-3 beta- (4-chlorophenyl) tropane and related substances thereof | 江苏省原子医学研究所 | 2023-09-22 | — | — | CN | claimed |
| EP-0905135-A2 | Cocaine receptor binding ligands | RESEARCH TRIANGLE INSTITUTE (US) | 1999-03-31 | — | — | EP | claimed |
| CN-114487184-B | Method for determining 2 beta-methyl ester-3 beta- (4-chlorophenyl) tropane and related substances thereof | 江苏省原子医学研究所 | 2023-09-22 | — | — | CN | disclosed |
| CN-114487184-B | Method for determining 2 beta-methyl ester-3 beta- (4-chlorophenyl) tropane and related substances thereof | 江苏省原子医学研究所 | 2023-09-22 | — | — | CN | disclosed |
| US-20170115259-A1 | HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR ANALYZING IMAGING AGENT, PRECURSOR OF IMAGING AGENT, OR INTERMEDIATE OF IMAGING AGENT | Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C. (TW) | 2017-04-27 | — | — | US | disclosed |
| US-20080153870-A1 | COCAINE RECEPTOR BINDING LIGANDS | RESEARCH TRIANGLE INSTITUTE (US) | 2008-06-26 | — | — | US | disclosed |
| US-7291737-B2 | Cocaine receptor binding ligands | RESEARCH TRIANGLE INSTITUTE (US) | 2007-11-06 | — | — | US | disclosed |
| US-7189737-B2 | Cocaine receptor binding ligands | RESEARCH TRIANGLE INSTITUTE (US) | 2007-03-13 | — | — | US | disclosed |
| EP-0905135-B1 | Cocaine receptor binding ligands | RES TRIANGLE INST (US) | 2006-09-06 | — | — | EP | disclosed |
| US-20050197360-A1 | Cocaine receptor binding ligands | RESEARCH TRIANGLE INSTITUTE (US) | 2005-09-08 | — | — | US | disclosed |
| US-6706880-B2 | USED AS IMAGING OR PHARMACEUTICAL AGENTS, IN THE DIAGNOSIS AND THERAPY OF DRUG ADDICTION, DEPRESSION, ANOREXIA AND NEURODEGENERATIVE DISEASES | RESEARCH TRIANGLE INSTITUTE | 2004-03-16 | — | — | US | disclosed |
| EP-1079833-A1 | COCAINE RECEPTOR BINDING LIGANDS | RESEARCH TRIANGLE INSTITUTE (US) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999061023-A1 | COCAINE RECEPTOR BINDING LIGANDS | RESEARCH TRIANGLE INSTITUTE (US) | 1999-12-02 | — | — | WO | disclosed |
| US-5935953-A | TROPANE DERIVATIVES AS INHIBITORS TO REDUCE THE FEEDING OF AND DELAYING THE MATURATION OF THE INSECTS AND PESTS; INHIBITORS OF A PHENYLETHANOLAMINE, E.G.OCTOPAMINE, REUPTAKE TRANSPORTER; PESTICIDES; PESTISTATS; INSECTICIDES | RESEARCH TRIANGLE INSTITUTE (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0644775-B1 | Cocaine Receptor Binding Ligands | RES TRIANGLE INST (US) | 1999-08-04 | — | — | EP | disclosed |
| EP-0905135-A2 | Cocaine receptor binding ligands | RESEARCH TRIANGLE INSTITUTE (US) | 1999-03-31 | — | — | EP | disclosed |
| US-5736123-A | TRIALKYLTIN CHEMICAL INTERMEDIATES | RESEARCH TRIANGLE INSTITUTE (US) | 1998-04-07 | — | — | US | disclosed |
| US-5496953-A | DOPAMINE TRANSPORTER SITES, RADIOACTIVE, DIAGNOSIS, IMAGING, NORTROPANE DERIVATIVES | RESEARCH TRIANGLE INSTITUTE (US) | 1996-03-05 | — | — | US | disclosed |
| US-5380848-A | 8-azabicyclo(3.2.1)octanes | RESEARCH TRIANGLE INSTITUTE (US) | 1995-01-10 | — | — | US | disclosed |
| WO-1993009814-A1 | COCAINE RECEPTOR BINDING LIGANDS | RESEARCH TRIANGLE INSTITUTE (US) | 1993-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153870-A1 | COCAINE RECEPTOR BINDING LIGANDS | SLC18A2, SLC6A3, SLC18A3 | SLC6A3 2/4885SLC6A2 4/4885SLC6A4 11/4885 |
| US-20050197360-A1 | Cocaine receptor binding ligands | SLC18A2, SLC6A3, SLC18A3 | SLC6A3 2/4885SLC6A2 4/4885SLC6A4 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.