Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 2/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | APP | P05067 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | OSBP | P22059 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL742786 | 1.00 | ACHE (0.55) | ACHEBACE1PTPN1PPARGPPARA | |
| SCHEMBL30249555 | 1.00 | ACHE (0.55) | ACHEBACE1PTPN1PPARGPPARA | |
| SCHEMBL11305967 | 1.00 | ACHE (0.55) | ACHEBACE1PTPN1PPARGPPARA | |
| SCHEMBL11305964 | 1.00 | ACHE (0.55) | ACHEBACE1PTPN1PPARGPPARA | |
| SCHEMBL5823579 | 0.98 | ACHE (0.56) | ACHEBACE1PTPN1PPARGPPARA | |
| SCHEMBL15970483 | 0.88 | ACHE (0.56) | ACHEBACE1PTPN1PPARGPPARA | |
| SCHEMBL15970519 | 0.88 | ACHE (0.56) | ACHEBACE1PTPN1PPARGPPARA | |
| SCHEMBL14248440 | 0.88 | ACHE (0.56) | ACHEBACE1PTPN1PPARGPPARA | |
| SCHEMBL30555857 | 0.88 | ACHE (0.56) | ACHEBACE1PTPN1PPARGPPARA | |
| SCHEMBL31611507 | 0.88 | ACHE (0.56) | ACHEBACE1PTPN1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10877035-B2 | Advanced drug development and manufacturing | ICAGEN, LLC (US) | 2020-12-29 | — | — | US | disclosed |
| US-20150309021-A1 | Advanced Drug Development and Manufacturing | LOS ALAMOS NATIONAL SECURITY, LLC | 2015-10-29 | — | — | US | disclosed |
| EP-2511844-B1 | X-ray microscope | XRPRO SCIENCES INC (US) | 2015-08-12 | — | — | EP | disclosed |
| EP-2511844-A2 | Advanced drug development and manufacturing | Los Alamos National Security, LLC (US) | 2012-10-17 | — | — | EP | disclosed |
| US-20080220441-A1 | Advanced drug development and manufacturing | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-09-11 | — | — | US | disclosed |