Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 8/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | CSF1R | P07333 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KLK7 | P49862 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5007830 | 0.83 | MAPK14 (0.72) | BRAFMEN1KMT2ACSF1RALDH1A1 | |
| SCHEMBL5004469 | 0.83 | BRAF (0.83) | BRAFMEN1KMT2ACSF1RNPC1 | |
| SCHEMBL5007906 | 0.83 | BRAF (0.69) | BRAFMEN1KMT2ACSF1RNPC1 | |
| SCHEMBL5509423 | 0.80 | CSF1R (0.70) | BRAFMEN1KMT2ACSF1RNPC1 | |
| SCHEMBL5004904 | 0.79 | BRAF (0.76) | BRAFCYP2C9RAF1 | |
| SCHEMBL5009705 | 0.79 | BRAF (0.73) | BRAFMEN1KMT2ACSF1RNPC1 | |
| SCHEMBL16621265 | 0.77 | HSF1 (0.79) | BRAFMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5009701 | 0.77 | BRAF (0.61) | BRAFMEN1KMT2ACSF1RNPC1 | |
| Hydrochloric Acid SCHEMBL5005019 | 0.76 | KMT2A (0.68) | BRAFMEN1KMT2ANPC1RAB9A | |
| SCHEMBL6979265 | 0.76 | BRAF (0.77) | BRAFCSF1RNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207616-A1 | Quinoxalines as B Baf Inhhibitors | ASTRAZENECA AB (SE) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207616-A1 | Quinoxalines as B Baf Inhhibitors | BRAF, NRAS, ARAF | BRAF 1/4885MEN1 671/4885KMT2A 1967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.