SCHEMBL500266

SCHEMBL500266

C=CC(=O)OCCN(C(C)(C)C)C(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.50
ALDH1A1 P00352 4/20 0.50
TP53 P04637 3/20 0.50
HIF1A Q16665 3/20 0.50
CYP3A4 P08684 2/20 0.50
HPGD P15428 1/20 0.50
HSD17B10 Q99714 1/20 0.50
THRB P10828 2/20 0.46
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRM3 P20309 1/20 0.31
CHRNA4 P43681 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1233784 0.86 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL13451143 0.85 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL16295212 0.83 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8605068 0.83 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL17522091 0.80 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
Chloromethane SCHEMBL127030 0.78 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL13451145 0.78 TSHR (0.47) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL5707610 0.78 TSHR (0.56) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL15115 0.78 TSHR (0.56) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7050406 0.77 TSHR (0.60) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112533910-A Monoethylenically unsaturated monomers and their use 博斯蒂克股份公司 2021-03-19 CN claimed
EP-1675880-B1 METHOD FOR PARTIAL OR TOTAL OXIDATION OF ONE OR SEVERAL THIOCARBONYLTHIO ENDS OF A POLYMER OBTAINED BY RADICAL POLYMERISATION CONTROLLED BY REVERSIBLE ADDITION-CLEAVAGE RHODIA CHIMIE SA (FR) 2019-03-13 EP claimed
US-7728088-B2 Synthesis of statistical microgels by means of controlled radical polymerisation RHODIA OPERATIONS (FR) 2010-06-01 US claimed
EP-1527105-B1 SYNTHESIS OF STATISTICAL MICROGELS BY MEANS OF CONTROLLED RADICAL POLYMERISATION RHODIA CHIMIE SA (FR) 2009-02-25 EP claimed
US-7473740-B2 Oxidizing one or more thiocarbonylthio ends of a polymer resulting from a radical polymerization controlled by reversible addition-fragmentation using thiocarbonylthio by reacting with ozone RHODIA CHIMIE (FR) 2009-01-06 US claimed
EP-1397403-B1 COPOLYMER WITH SURFACTANT BLOCKS PREPARED BY CONTROLLED FREE RADICAL POLYMERISATION RHODIA CHIMIE SA (FR) 2008-03-12 EP claimed
EP-1419181-B1 PROCESS FOR THE PREPARATION OF LATICES USING BLOCK COPOLYMERS AS SURFACTANTS RHODIA (US) 2007-03-14 EP claimed
US-20070027266-A1 Oxidizing one or more thiocarbonylthio ends of a polymer resulting from a radical polymerization controlled by reversible addition-fragmentation using thiocarbonylthio by reacting with ozone SPECIALTY OPERATIONS FRANCE (FR) 2007-02-01 US claimed
US-20060106178-A1 Synthesis of statistical microgels by means of controlled radical polymerisation RHODIA CHIMIE (FR) 2006-05-18 US claimed
EP-1123360-B1 COATING COMPOSITIONS CONTAINING FUNCTIONALISED SILICONES RHODIA CHIMIE SA (FR) 2004-12-15 EP claimed
US-6590026-B1 Epoxyfunctionalized polysiloxane emulsion, latex, and mineral filler; paints, coatings RHODIA CHIMIE (FR) 2003-07-08 US claimed
US-20030013799-A1 Aqueous suspension of nanoparticles comprising an agrochemical active ingredient CROOKS REGAN (US) 2003-01-16 US claimed
US-20020198347-A1 Surface-active block copolymers prepared by controlled radical polymerization ADAM HERVE (US) 2002-12-26 US claimed
US-20020198316-A1 Process for the preparation of latices using block copolymers as surfactants RHODIA OPERATIONS (FR) 2002-12-26 US claimed
WO-2002090392-A1 PROCESS FOR THE PREPARATION OF LATICES USING BLOCK COPOLYMERS AS SURFACTANTS RHODIA CHIMIE (FR) 2002-11-14 WO claimed
WO-2002082900-A1 AQEUOUS SUSPENSION OF NANOPARTICLES COMPRISING AN AGROCHEMICAL ACTIVE INGREDIENT RHODIA INC. (US) 2002-10-24 WO claimed
US-6455132-B1 NEUTRALIZED COPOLYMER OF (METH)ACRYLATE AND/OR (METH)ACRYLAMIDE HAVING TERTIARY AMINE GROUPS; NONIONIC OR CATIONIC SURFACTANT, AND WATER; INK JETTING KODAK POLYCHROME GRAPHICS LLC 2002-09-24 US claimed
US-6245421-B1 THERMOPLASTIC INK RECEIVERS KODAK POLYCHROME GRAPHICS LLC 2001-06-12 US claimed
WO-2000046036-A1 MATERIAL FOR LITHOGRAPHIC PRINTING AND INK-JET PROCESS FOR ITS PREPARATION SUN CHEMICAL CORPORATION (US) 2000-08-10 WO claimed
WO-2000046035-A1 PRINTABLE MEDIA AND METHOD FOR ITS PREPARATION BY INK-JET PRINTING SUN CHEMICAL CORPORATION (US) 2000-08-10 WO claimed