SCHEMBL500322

SCHEMBL500322

Cc1cn[c]nc1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17925768 0.74
SCHEMBL1885205 0.74
SCHEMBL1586085 0.74
SCHEMBL1849503 0.74
SCHEMBL1885204 0.74
SCHEMBL1856198 0.74
SCHEMBL1879648 0.70 AOC1 (0.31)
SCHEMBL1881681 0.70
SCHEMBL558255 0.70
SCHEMBL1881680 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 318 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230416205-A1 COMPOUNDS, COMPOSITIONS, AND METHODS TENVIE THERAPEUTICS, INC. 2023-12-28 US claimed
US-20230365557-A1 IMIDAZOPYRIDINYL COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE DISORDERS 1ST Biotherapeutics, Inc. (KR) 2023-11-16 US claimed
US-11802126-B2 Imidazopyridinyl compounds and use thereof for treatment of neurodegenerative disorders 1ST Biotherapeutics, Inc. (KR) 2023-10-31 US claimed
EP-4247376-A1 COMPOUNDS, COMPOSITIONS, AND METHODS Denali Therapeutics Inc. (US) 2023-09-27 EP claimed
CN-116507608-A Compounds, compositions, and methods 戴纳立制药公司 2023-07-28 CN claimed
EP-3856737-B1 HETEROCYCLYL COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE HOFFMANN LA ROCHE (CH) 2023-05-17 EP claimed
EP-3692023-B1 BENZOTHIAZOL COMPOUNDS AND METHODS USING THE SAME FOR TREATING NEURODEGENERATIVE DISORDERS 1ST BIOTHERAPEUTICS INC (KR) 2023-05-17 EP claimed
WO-2022109268-A1 COMPOUNDS, COMPOSITIONS, AND METHODS DENALI THERAPEUTICS INC. (US) 2022-05-27 WO claimed
EP-3927706-A1 IMIDAZOPYRIDINYL COMPOUNDS AND USE THEREOF FOR TREATMENT OF PROLIFERATIVE DISORDERS 1st Biotherapeutics, Inc. (KR) 2021-12-29 EP claimed
EP-3927705-A1 IMIDAZOPYRIDINYL COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE DISORDERS 1st Biotherapeutics, Inc. (KR) 2021-12-29 EP claimed
EP-0417057-A2 Heterocyclic thiol-based sulfenimide compounds and rubber compositions containing them MONSANTO COMPANY (US) 1991-03-13 EP claimed
EP-0177728-B1 ARPHAMENINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENT ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1989-05-31 EP claimed
EP-0240986-A2 D-Nor-7-ergoline derivatives, process for preparing them, pharmaceutical composition and use FARMITALIA CARLO ERBA S.r.l. (IT) 1987-10-14 EP claimed
US-4661495-A ENZYME INHIBITORS ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1987-04-28 US claimed
EP-0214823-A2 Alkylamide derivatives with H2-receptor antagonistic and cytoprotective action FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) 1987-03-18 EP claimed
EP-0177728-A2 Arphamenine derivatives, a process for their preparation and their use as medicament ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1986-04-16 EP claimed
US-4323569-A β-Lactam anti-bacterial, compositions containing them and a process for their preparation BEECHAM GROUP LIMITED (GB) 1982-04-06 US claimed
EP-0008514-B1 BETA-LACTAM ANTI-BACTERIALS, COMPOSITIONS CONTAINING THEM AND A PROCESS FOR THEIR PREPARATION BEECHAM GROUP PLC (GB) 1982-01-20 EP claimed
EP-0008514-A1 Beta-lactam anti-bacterials, compositions containing them and a process for their preparation BEECHAM GROUP PLC (GB) 1980-03-05 EP claimed
US-4136253-A ANTIBIOTICS PFIZER INC. (US) 1979-01-23 US claimed