SCHEMBL500473

SCHEMBL500473

O=C1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.56
ACHE P22303 2/20 0.56
HTR1A P08908 1/20 0.44
LMNA P02545 1/20 0.44
TACR2 P21452 3/20 0.43
NT5E P21589 1/20 0.43
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
SSTR1 P30872 1/20 0.40
SSTR2 P30874 1/20 0.40
SSTR4 P31391 1/20 0.40
SSTR3 P32745 1/20 0.40
SSTR5 P35346 1/20 0.40
PTPN1 P18031 5/20 0.39
CDC25B P30305 5/20 0.39
PTPN2 P17706 2/20 0.39
PTPN6 P29350 2/20 0.39
PTPN11 Q06124 2/20 0.39
PDPK1 O15530 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2174263 1.00 BCHE (0.56) BCHEACHEHTR1ALMNATACR2
SCHEMBL13112800 1.00 BCHE (0.56) BCHEACHEHTR1ALMNATACR2
SCHEMBL13956209 1.00 BCHE (0.56) BCHEACHEHTR1ALMNATACR2
SCHEMBL16027502 1.00 BCHE (0.56) BCHEACHEHTR1ALMNATACR2
SCHEMBL12407911 1.00 BCHE (0.56) BCHEACHEHTR1ALMNATACR2
SCHEMBL1087871 1.00 BCHE (0.56) BCHEACHEHTR1ALMNATACR2
SCHEMBL18511226 1.00 BCHE (0.56) BCHEACHEHTR1ALMNATACR2
SCHEMBL22129916 1.00 BCHE (0.56) BCHEACHEHTR1ALMNATACR2
SCHEMBL22330780 1.00 BCHE (0.56) BCHEACHEHTR1ALMNATACR2
SCHEMBL13956220 1.00 BCHE (0.56) BCHEACHEHTR1ALMNATACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57154196-A None JP disclosed
EP-4717316-A2 ANTI-EGFR ANTIBODY-DRUG CONJUGATES AbbVie Inc. (US) 2026-04-01 EP disclosed
US-20250263491-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2025-08-21 US disclosed
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2025-07-03 US disclosed
US-12324812-B2 Glucopyranosyl derivatives and their uses SUNSHINE LAKE PHARMA CO., LTD. (CN) 2025-06-10 US disclosed
US-20250177374-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same ABBVIE INC (US) 2025-06-05 US disclosed
US-20250170263-A1 ANTI-EGFR ANTIBODY-DRUG CONJUGATES ABBVIE INC (US) 2025-05-29 US disclosed
CN-119306684-A Key intermediate for preparing SGLTs inhibitor and preparation method thereof 宜昌东阳光长江药业股份有限公司 2025-01-14 CN disclosed
US-20240199745-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2024-06-20 US disclosed
EP-4364754-A2 ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES AbbVie Inc. (US) 2024-05-08 EP disclosed
EP-1553094-A1 AZULENE DERIVATIVES AND SALTS THEREOF YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 2005-07-13 EP disclosed
US-20050124555-A1 Azulene derivatives and salts thereof ASTELLAS PHARMA INC. (JP) 2005-06-09 US disclosed
EP-0260121-B1 INOSOSE DERIVATIVES, PRODUCTION AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 1993-03-10 EP disclosed
EP-0240175-B1 INOSOSE DERIVATIVES AND PRODUCTION THEREOF Takeda Chemical Industries, Ltd. (JP) 1991-10-16 EP disclosed
US-5004838-A Inosose derivatives, production and use thereof TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-04-02 US disclosed
US-4898986-A Inosose derivatives, production and use thereof TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-02-06 US disclosed
US-4824943-A Inosose derivatives and production thereof TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-04-25 US disclosed
EP-0260121-A2 Inosose derivatives, production and use thereof Takeda Chemical Industries, Ltd. (JP) 1988-03-16 EP disclosed
EP-0240175-A1 Inosose derivatives and production thereof Takeda Chemical Industries, Ltd. (JP) 1987-10-07 EP disclosed
JP-S57154196-A PREPARATION OF GLYCOSYLIDENE ACETALS YOSHIMURA TOSHITSUGU 1982-09-22 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250170263-A1 ANTI-EGFR ANTIBODY-DRUG CONJUGATES EGFR, ERBB3, ERBB2 BCHE 1409/4885ACHE 4603/4885HTR1A 4011/4885
US-20050124555-A1 Azulene derivatives and salts thereof SLC5A1, SLC5A2, SLC2A1 BCHE 3675/4885ACHE 4737/4885HTR1A 2526/4885
US-20240199745-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES EGFR, ERBB2, ERBB3 BCHE 2479/4885ACHE 4793/4885HTR1A 3825/4885
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES EGFR, ERBB2, ERBB3 BCHE 2479/4885ACHE 4793/4885HTR1A 3825/4885
US-20250263491-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES EGFR, ERBB2, ERBB3 BCHE 2479/4885ACHE 4793/4885HTR1A 3825/4885
US-20250177374-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same BCL2, BAX, BCL9 BCHE 3784/4885ACHE 4652/4885HTR1A 4520/4885
US-12324812-B2 Glucopyranosyl derivatives and their uses SLC5A1, SLC5A2, UGGT1 BCHE 3608/4885ACHE 3875/4885HTR1A 2648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.