Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | TPO | P07202 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11778511 | 0.87 | PNMT (0.52) | CYP3A4ALOX15KMT2AMEN1HPGD | |
| SCHEMBL9656059 | 0.85 | CYP3A4 (0.58) | CYP3A4ALOX15KMT2AMEN1HPGD | |
| SCHEMBL9658439 | 0.81 | CYP3A4 (0.42) | CYP3A4ALOX15KMT2AMEN1HPGD | |
| SCHEMBL6839208 | 0.80 | HTR2A (0.48) | CYP3A4TSHRALDH1A1TDP1BCL2 | |
| SCHEMBL28691380 | 0.80 | CYP3A4 (0.56) | CYP3A4ALOX15KMT2AMEN1HPGD | |
| SCHEMBL3618843 | 0.80 | MEN1 (0.67) | CYP3A4ALOX15KMT2AMEN1HPGD | |
| SCHEMBL3251975 | 0.79 | CYP3A4 (0.47) | CYP3A4ALOX15KMT2AMEN1HPGD | |
| SCHEMBL22898008 | 0.79 | TSHR (0.50) | CYP3A4ALOX15KMT2AMEN1HPGD | |
| SCHEMBL22232424 | 0.78 | CYP3A4 (0.50) | CYP3A4ALOX15KMT2AMEN1HPGD | |
| SCHEMBL11030384 | 0.77 | CYP3A4 (0.62) | CYP3A4ALOX15KMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58225017-A | — | — | None | — | — | JP | disclosed |
| CN-115433346-B | Palladium catalyst based on phenanthrenequinone alpha-diamine, and preparation method and application thereof | 武汉工程大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-115433346-A | Phenanthrenequinone alpha-diamine-based palladium catalyst and preparation method and application thereof | 武汉工程大学 | 2022-12-06 | — | — | CN | disclosed |
| US-7414063-B2 | Inhibitors of Akt (protein kinase B) | ELI LILLY AND COMPANY (US) | 2008-08-19 | — | — | US | disclosed |
| US-20070043040-A1 | Inhibitors of akt (protein kinase b) | ELI LILLY AND COMPANY | 2007-02-22 | — | — | US | disclosed |
| CN-1768040-A | Isoquinoline-5-sulfonic acid amides as inhibitors of AKT (protein kinase B) | LILLY CO ELI (US) | 2006-05-03 | — | — | CN | disclosed |
| EP-1611105-A1 | ISOQUINOLINE-5-SULFONIC ACID AMIDES AS INHIBITORS OF AKT (PROTEIN KINASE B) | ELI LILLY AND COMPANY (US) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004094386-A1 | ISOQUINOLINE-5-SULFONIC ACID AMIDES AS INHIBITORS OF AKT (PROTEIN KINASE B) | ELI LILLY AND COMPANY (US) | 2004-11-04 | — | — | WO | disclosed |
| EP-0301549-B1 | 1-[2-(Phenylmethyl)phenyl]-piperazine compounds, a process for preparing them and pharmaceutical compostions containing them | FERRER INTERNACIONAL, S.A. (ES) | 1992-10-28 | — | — | EP | disclosed |
| US-5091415-A | Antiulcer, antisecretory agents | PIERRE FABRE MEDICAMENT (FR) | 1992-02-25 | — | — | US | disclosed |
| US-5025015-A | Antisecretory and antiulcer agents | PIERRE FABRE MEDICAMENT (FR) | 1991-06-18 | — | — | US | disclosed |
| US-4859675-A | 1-[2-(phenylmethyl) phenyl]piperazines as antidepressants | FERRER INTERNACIONAL S.A. (ES) | 1989-08-22 | — | — | US | disclosed |
| EP-0301549-A1 | 1-[2-(Phenylmethyl)phenyl]-piperazine compounds, a process for preparing them and pharmaceutical compostions containing them | FERRER INTERNACIONAL, S.A. (ES) | 1989-02-01 | — | — | EP | disclosed |
| EP-0048998-B1 | ISONICOTINANILIDE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND PLANT GROWTH REGULATOR CONTAINING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1985-01-09 | — | — | EP | disclosed |
| JP-S58225017-A | AGENT FOR ELIMINATING CANCER | CHUGAI PHARMACEUT CO LTD | 1983-12-27 | — | — | JP | disclosed |
| US-4377407-A | Isonicotinanilide derivatives, plant growth regulating compositions and use | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1983-03-22 | — | — | US | disclosed |
| US-3992400-A | 1-(α-Phenyl-o-tolyl)imidazoles | THE UPJOHN COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3941802-A | 2-(Imidazol-1-yl)benzophenones | THE UPJOHN COMPANY (US) | 1976-03-02 | — | — | US | disclosed |
| US-3941803-A | 2-(Imidazol-1-yl)benzophenones | THE UPJOHN COMPANY (US) | 1976-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043040-A1 | Inhibitors of akt (protein kinase b) | AKT1, AKT2, BRAF | CYP3A4 3139/4885ALOX15 4158/4885KMT2A 2622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.