SCHEMBL500727

SCHEMBL500727

C1=NC(c2ccccc2)CO1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.46
TSHR P16473 1/20 0.43
MAPT P10636 2/20 0.38
MAOB P27338 8/20 0.37
MAOA P21397 7/20 0.37
KDM1A O60341 5/20 0.37
CYP2C19 P33261 4/20 0.37
CYP2B6 P20813 3/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2D6 P10635 2/20 0.37
CYP2C9 P11712 2/20 0.37
LMNA P02545 2/20 0.37
CYP3A4 P08684 1/20 0.37
HTR1A P08908 1/20 0.37
ADRA2A P08913 1/20 0.37
CYP2A6 P11509 1/20 0.37
SLC6A2 P23975 1/20 0.37
HTR2C P28335 1/20 0.37
ADRA1A P35348 1/20 0.37
DRD3 P35462 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3354178 1.00 TAAR1 (0.46) TAAR1TSHRMAPTMAOBMAOA
SCHEMBL8055813 1.00 TAAR1 (0.46) TAAR1TSHRMAPTMAOBMAOA
Dibenzofuran SCHEMBL28885932 0.86 TAAR1 (0.37) TAAR1TSHRMAPTMAOACYP2C9
SCHEMBL28563511 0.79 KDM1A (0.37) MAPTKDM1ACYP2C9LMNACYP3A4
SCHEMBL15842791 0.76 TAAR1 (0.35) TAAR1TSHRMAPT
SCHEMBL15842834 0.74 TAAR1 (0.33) TAAR1TSHRMAPT
SCHEMBL20385798 0.74 HTR2C (0.46) KDM1AHTR1AHTR2CDRD3RCOR1
SCHEMBL14044885 0.74 HTR2C (0.45) TAAR1KDM1ALMNAHTR2CADRA1A
SCHEMBL28867385 0.72 TAAR1 (0.51) TAAR1TSHRMAOBMAOAKDM1A
SCHEMBL20385738 0.72 TAAR1 (0.51) TAAR1TSHRMAOBMAOAKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 503 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040461-A Spirobarbitudes compound, preparation method and application 北京工业大学 2025-05-27 CN claimed
CN-120040462-A Spiropyrazinone compound, preparation method and application 北京工业大学 2025-05-27 CN claimed
CN-118307410-A Preparation method of chiral secondary alcohol compound 武汉大学 2024-07-09 CN claimed
CN-116478447-B Modified regenerant of polyester elastomer and application thereof 苏州申赛新材料有限公司 2023-08-29 CN claimed
CN-115894299-A Preparation method of axial chiral carbamate 华南理工大学 2023-04-04 CN claimed
CN-115894232-A Asymmetric synthesis method of nickel-catalyzed carbon-based alpha-ester 南京师范大学 2023-04-04 CN claimed
CN-111548329-B Preparation method of brivaracetam 浙江乐普药业股份有限公司 2022-06-17 CN claimed
CN-111072583-B Biaryl axial chiral heterocyclic sulfide and synthesis method and application thereof 浙江工业大学 2022-03-18 CN claimed
CN-112174995-B Double-silicon compound, preparation method and application thereof 武汉大学 2021-12-03 CN claimed
CN-113698637-A Full-biodegradable mulching film material for tobacco planting and preparation method thereof 兰州鑫银环橡塑制品有限公司 2021-11-26 CN claimed
CN-103627151-A Polyester full-biodegradable mulch film ZHEJIANG BOHAI HEALTH PRODUCTS CO LTD 2014-03-12 CN claimed
CN-102731332-A Synthetic method of alpha-chiral amino acid derivatives UNIV SOUTH CHINA TECH 2012-10-17 CN claimed
US-20120141762-A1 CONDUCTIVE MASTERBATCHES AND CONDUCTIVE MONOFILAMENTS TAIWAN TEXTILE RESEARCH INSTITUTE (TW) 2012-06-07 US claimed
US-20100143714-A1 CONDUCTIVE MASTERBATCHES AND CONDUCTIVE MONOFILAMENTS TAIWAN TEXTILE RESEARCH INSTITUTE (TW) 2010-06-10 US claimed
US-7524594-B2 Photosensitive dielectric resin compositions, films formed therefrom and semiconductor and display devices encompassing such films PROMERUS LLC (US) 2009-04-28 US claimed
CN-100448489-C Flame-retardant polyester artificial hair KANEGAFUCHI CHEMICAL IND (JP) 2009-01-07 CN claimed
EP-1778759-B1 PHOTOSENSITIVE DIELECTRIC RESIN COMPOSITIONS AND THEIR USES PROMERUS LLC (US) 2008-11-12 EP claimed
EP-1778759-A1 PHOTOSENSITIVE DIELECTRIC RESIN COMPOSITIONS AND THEIR USES Promerus, LLC (US) 2007-05-02 EP claimed
WO-2006017035-A1 PHOTOSENSITIVE DIELECTRIC RESIN COMPOSITIONS AND THEIR USES PROMERUS LLC (US) 2006-02-16 WO claimed
US-20060008734-A1 Photosensitive dielectric resin compositions, films formed therefrom and semiconductor and display devices encompassing such films SUMITOMO BAKELITE CO., LTD. (JP) 2006-01-12 US claimed