SCHEMBL50078

SCHEMBL50078

Cc1ccc([N]c2ccc(C)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 6/20 0.57
TDP1 Q9NUW8 2/20 0.57
HTR3E A5X5Y0 2/20 0.50
HTR3B O95264 2/20 0.50
HTR3A P46098 2/20 0.50
HTR3D Q70Z44 2/20 0.50
HTR3C Q8WXA8 2/20 0.50
SLC22A2 O15244 1/20 0.50
SLC22A1 O15245 1/20 0.50
SLC22A3 O75751 1/20 0.50
PLAU P00749 1/20 0.50
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2A6 P11509 1/20 0.43
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MAPT P10636 2/20 0.42
MAPK1 P28482 2/20 0.42
STAT3 P40763 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL503321 0.88 ACHE (0.53) ACHETDP1HTR3EHTR3BHTR3A
SCHEMBL9066551 0.80
SCHEMBL255052 0.79 NPC1 (0.61) ACHETDP1HTR3EHTR3BHTR3A
SCHEMBL1405393 0.79 NPC1 (0.61) ACHETDP1HTR3EHTR3BHTR3A
SCHEMBL11693056 0.79 NPC1 (0.61) ACHETDP1HTR3EHTR3BHTR3A
SCHEMBL17446281 0.79 NPC1 (0.61) ACHETDP1HTR3EHTR3BHTR3A
SCHEMBL11693067 0.79 NPC1 (0.61) ACHETDP1HTR3EHTR3BHTR3A
SCHEMBL10350869 0.78 ACHE (0.47) ACHETDP1HTR3EHTR3BHTR3A
P-Xylene SCHEMBL28206161 0.76 ACHE (0.80) ACHETDP1HTR3EHTR3BHTR3A
P-Xylene SCHEMBL460348 0.76 ACHE (1.00) ACHETDP1CYP2A6ALDH1A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3506 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111153884-B Pi-system extended coumarin compound, preparation method thereof and application thereof as photoluminescence material 陕西师范大学 2023-02-03 CN claimed
CN-111153884-A Pi-system extended coumarin compound, preparation method thereof and application thereof as photoluminescence material 陕西师范大学 2020-05-15 CN claimed
EP-3026079-B1 ANTI-VIBRATION RUBBER COMPOSITION AND ANTI-VIBRATION RUBBER BRIDGESTONE CORP (JP) 2020-04-08 EP claimed
CN-107428769-B Heterocyclic compound and organic light-emitting element comprising same 株式会社LG化学 2020-03-27 CN claimed
EP-2379473-B1 DIACENAPHTHO[1,2-B:1',2'-K]CHRYSENE DERIVATIVE CANON KK (JP) 2017-02-22 EP claimed
US-20160152804-A1 ANTI-VIBRATION RUBBER COMPOSITION AND ANTI-VIBRATION RUBBER BRIDGESTONE CORPORATION (JP) 2016-06-02 US claimed
EP-3026079-A1 ANTI-VIBRATION RUBBER COMPOSITION AND ANTI-VIBRATION RUBBER Bridgestone Corporation (JP) 2016-06-01 EP claimed
US-9246104-B2 Fullerene derivative, method of manufacturing fullerene derivative and solar cell SHOWA DENKO K.K. (JP) 2016-01-26 US claimed
US-9028976-B2 Organic EL device FUTABA CORPORATION (JP) 2015-05-12 US claimed
EP-2675800-A1 FUNCTIONALIZED ANTHRACENE-CAPPED OLIGOTHIOPHENES AND ORGANIC SEMICONDUCTORS BASED ON THE SAME, USE THEREOF Institute Of Chemistry, Chinese Academy Of Sciences (CN) 2013-12-25 EP claimed
US-6346621-B1 INDOLE OR QUINOLINE COMPOUNDS SUBSTITUTED WITH AMINO COMPOUNDS ON NITROGEN TOSOH CORPORATION (JP) 2002-02-12 US claimed
US-6329084-B1 FLAT PANEL OR DISPLAY, BRIGHTNESS, RED COLOR, TERTRA(DIARYLAMINO) PERYLENES TOYO INK MFG. CO., LTD. (JP) 2001-12-11 US claimed
US-5698740-A ELECTROLUMINESCENCE TOYO INK MANUFACTURING CO., LTD. (JP) 1997-12-16 US claimed
US-5536949-A ELECTROPHOTOGRAPHIC PHOTORECEPTORS IDEMISTU KOSAN CO., LTD. (JP) 1996-07-16 US claimed
US-5486438-A MULTILAYER ELEMENT WITH ELECTROCONDUCTIVE SUBSTRATE WITH CHARGE GENERATING AND CHARGE TRANSPORT LAYERS RICOH COMPANY, LTD. (JP) 1996-01-23 US claimed
US-5436100-A A charge transport compound comprising a N-Ar-3-(diphenyl-amino)diphenylamine where Ar is a condensed or noncondensed polycyclic carbo ring; durability; heat resistance; mechanical shockproof RICOH COMPANY, LTD. (JP) 1995-07-25 US claimed
US-5356742-A Charge transfer materials in durable, low cost electrographic photoconductors RICOH COMPANY, LTD. (JP) 1994-10-18 US claimed
US-5334470-A Resistant to heat and mechanical shocks RICOH COMPANY, LTD. (JP) 1994-08-02 US claimed
US-5268246-A Charge generating and charge transportating layer RICOH COMPANY, LTD. (JP) 1993-12-07 US claimed
US-5158850-A Polyether compounds and electrophotographic photoconductor comprising one polyether compound RICOH COMPANY, LTD. (JP) 1992-10-27 US claimed