Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | RCE1 | Q9Y256 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5008832 | 1.00 | ALDH1A1 (0.58) | ALDH1A1CYP3A4HSD17B10HPGDTSHR | |
| SCHEMBL5013887 | 1.00 | ALDH1A1 (0.58) | ALDH1A1CYP3A4HSD17B10HPGDTSHR | |
| SCHEMBL22497391 | 1.00 | ALDH1A1 (0.58) | ALDH1A1CYP3A4HSD17B10HPGDTSHR | |
| SCHEMBL29390626 | 1.00 | ALDH1A1 (0.58) | ALDH1A1CYP3A4HSD17B10HPGDTSHR | |
| SCHEMBL29391698 | 1.00 | ALDH1A1 (0.58) | ALDH1A1CYP3A4HSD17B10HPGDTSHR | |
| SCHEMBL4924420 | 1.00 | ALDH1A1 (0.58) | ALDH1A1CYP3A4HSD17B10HPGDTSHR | |
| SCHEMBL28465029 | 1.00 | ALDH1A1 (0.58) | ALDH1A1CYP3A4HSD17B10HPGDTSHR | |
| SCHEMBL168479 | 0.98 | ALDH1A1 (0.61) | ALDH1A1CYP3A4HSD17B10HPGDTSHR | |
| SCHEMBL29364651 | 0.98 | ALDH1A1 (0.61) | ALDH1A1CYP3A4HSD17B10HPGDTSHR | |
| SCHEMBL31298085 | 0.98 | ALDH1A1 (0.61) | ALDH1A1CYP3A4HSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |