Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5005359 | 0.82 | MAPK3 (0.33) | FASN | |
| SCHEMBL5010502 | 0.80 | NAMPT (0.38) | FASNPDK2 | |
| SCHEMBL10140407 | 0.76 | FASN (0.35) | FASNJAK1PDK2 | |
| SCHEMBL18987570 | 0.74 | FASN (0.34) | FASNJAK1PDK2 | |
| SCHEMBL6648601 | 0.73 | — | — | |
| SCHEMBL19710833 | 0.72 | FASN (0.33) | FASNJAK1PDK2 | |
| SCHEMBL10119968 | 0.72 | FASN (0.33) | FASNJAK1PDK2 | |
| SCHEMBL14009873 | 0.72 | FASN (0.33) | FASNJAK1PDK2 | |
| SCHEMBL478842 | 0.72 | NR1H2 (0.51) | — | |
| SCHEMBL28982189 | 0.72 | CHRNB2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275085-A1 | Piperidine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-06 | — | — | US | claimed |
| US-20080275085-A1 | Piperidine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275085-A1 | Piperidine derivative and use thereof | TACR2, TACR1, PRLHR | FASN 4434/4885JAK1 1048/4885PDK2 3946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.