SCHEMBL5008797

SCHEMBL5008797

N=C(NSc1ccc(Cl)cc1)C1CN(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2Cl)=N1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 20/20 0.35
CNR2 P34972 12/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4215589 0.79 FLT1 (0.40) CNR1CNR2
SCHEMBL4359767 0.78 CNR1 (0.36) CNR1CNR2
SCHEMBL5008799 0.77 CNR1 (0.35) CNR1CNR2
SCHEMBL6335025 0.77 CNR1 (0.41) CNR1CNR2
SCHEMBL4220252 0.76 CNR1 (0.40) CNR1CNR2
Lithium Ion SCHEMBL4220249 0.76 CNR1 (0.40) CNR1CNR2
SCHEMBL4215280 0.72 CNR1 (0.56) CNR1CNR2
SCHEMBL4213596 0.72 CNR1 (0.53) CNR1CNR2
SCHEMBL4212958 0.71 CNR1 (0.43) CNR1CNR2
SCHEMBL13928742 0.69 CNR1 (0.36) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1725536-B1 IMIDAZOLINE DERIVATIVES HAVING CB1-ANTAGONISTIC ACTIVITY SOLVAY PHARM BV (NL) 2008-10-15 EP claimed