Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 16/20 | 0.35 |
| ▸ | CNR2 | P34972 | 10/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13928740 | 0.80 | F2 (0.40) | CNR1CNR2 | |
| SCHEMBL4215594 | 0.80 | F2 (0.40) | CNR1CNR2 | |
| SCHEMBL4359770 | 0.79 | CNR1 (0.36) | CNR1CNR2CYP3A4DPP4DPP8 | |
| SCHEMBL13928742 | 0.79 | CNR1 (0.36) | CNR1CNR2CYP3A4DPP4DPP8 | |
| SCHEMBL6335025 | 0.78 | CNR1 (0.41) | CNR1CNR2 | |
| SCHEMBL5008797 | 0.77 | CNR1 (0.35) | CNR1CNR2 | |
| SCHEMBL4220252 | 0.77 | CNR1 (0.40) | CNR1CNR2 | |
| Lithium Ion SCHEMBL4220249 | 0.77 | CNR1 (0.40) | CNR1CNR2 | |
| SCHEMBL4215991 | 0.76 | CNR1 (0.41) | CNR1CNR2CYP3A4DPP4DPP8 | |
| SCHEMBL13928738 | 0.76 | CNR1 (0.41) | CNR1CNR2CYP3A4DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725536-B1 | IMIDAZOLINE DERIVATIVES HAVING CB1-ANTAGONISTIC ACTIVITY | SOLVAY PHARM BV (NL) | 2008-10-15 | — | — | EP | claimed |