Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.46 |
| ▸ | ESR1 | P03372 | 11/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Betanaphthol SCHEMBL16236791 | 0.92 | CYP1A2 (0.65) | CYP1A2ESR2ESR1CYP3A4ALOX15 | |
| SCHEMBL1451816 | 0.91 | CYP1A2 (0.50) | CYP1A2ESR2ESR1CYP3A4ALOX15 | |
| SCHEMBL129202 | 0.77 | — | — | |
| SCHEMBL69484 | 0.77 | CYP1A2 (0.77) | CYP1A2ESR2ESR1CYP3A4ALOX15 | |
| SCHEMBL29364786 | 0.77 | CYP1A2 (0.77) | CYP1A2ESR2ESR1CYP3A4ALOX15 | |
| SCHEMBL627219 | 0.77 | CYP1A2 (0.77) | CYP1A2ESR2ESR1CYP3A4ALOX15 | |
| SCHEMBL3135465 | 0.76 | LCK (0.34) | CYP1A2CYP3A4ALOX15HIF1AHSD17B10 | |
| SCHEMBL70257 | 0.75 | — | — | |
| SCHEMBL559813 | 0.75 | — | — | |
| Hydroquinone SCHEMBL6689552 | 0.74 | ESR2 (0.74) | CYP1A2ESR2ESR1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 411 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820087-A | Preparation method of bisphenol A diglycerol ether compound | 中国石油化工股份有限公司 | 2024-04-05 | — | — | CN | claimed |
| US-20210371398-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS MER INHIBITORS | DONG A SOCIO HOLDINGS CO LTD (KR) | 2021-12-02 | — | — | US | claimed |
| US-20190315716-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS MER INHIBITORS | DONG-A ST CO., LTD. (KR) | 2019-10-17 | — | — | US | claimed |
| EP-3523292-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS MER INHIBITORS | Dong-A Socio Holdings Co., Ltd. (KR) | 2019-08-14 | — | — | EP | claimed |
| WO-2018071343-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS MER INHIBITORS | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2018-04-19 | — | — | WO | claimed |
| CN-104744460-B | β carbolines, dihydro β carbolines and tetrahydro-beta-carboline alcaloid-derivatives and preparation method thereof and the application in terms of preventing and treating plant virus, sterilization, desinsection | 南开大学 | 2017-06-16 | — | — | CN | claimed |
| EP-2576543-B1 | PYRAZOLE COMPOUNDS AS SIGMA RECEPTOR INHIBITORS | ESTEVE LABOR DR (ES) | 2016-12-21 | — | — | EP | claimed |
| US-9181195-B2 | Sigma receptor inhibitors | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2015-11-10 | — | — | US | claimed |
| US-20130158029-A1 | SIGMA RECEPTOR INHIBITORS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2013-06-20 | — | — | US | claimed |
| EP-2576543-A1 | PYRAZOLE COMPOUNDS AS SIGMA RECEPTOR INHIBITORS | Laboratorios del Dr. Esteve S.A. (ES) | 2013-04-10 | — | — | EP | claimed |
| US-5004832-A | Heating lactone precursor in protic polar or aprotic dipolar solvent in presence of substance with high dielectric constant | ZAMBON S.P.A. (IT) | 1991-04-02 | — | — | US | claimed |
| EP-0398288-A2 | Process for preparing optically active 2-arylalkanoic acids, in particular 2-arylpropionic acids | MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) | 1990-11-22 | — | — | EP | claimed |
| EP-0380316-A2 | Preparation of alpha-methylareneacetic acids | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1990-08-01 | — | — | EP | claimed |
| EP-0175535-B1 | MAGNETIC COMPOSITE | POLYPLASTICS CO. LTD. (JP) | 1990-08-01 | — | — | EP | claimed |
| US-4888433-A | CHIRAL HALOGENATED KETALS WHICH UNDERGO STEREOSELECTIVE REARRANGEMENT | ZAMBON, S.P.A. (IT) | 1989-12-19 | — | — | US | claimed |
| US-4845243-A | Intermediates and their use in the synthesis of organic compounds | ZAMBON S.P.A. (IT) | 1989-07-04 | — | — | US | claimed |
| US-4824970-A | LACTONES, ANALGESICS | ZAMBON SPA (IT) | 1989-04-25 | — | — | US | claimed |
| EP-0272644-A2 | Intermediates and their use in the synthesis of organic compounds | ZAMBON S.p.A. (IT) | 1988-06-29 | — | — | EP | claimed |
| US-4734507-A | Optically active ketals, processes for their preparation and their use in the synthesis of alpha-arylalkanoic acids | ZAMBON S.P.A. (IT) | 1988-03-29 | — | — | US | claimed |
| EP-0227078-A1 | Process for preparing (S)-alpha-methylarylacetic acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1987-07-01 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315716-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS MER INHIBITORS | MERTK, RET, ERBB4 | CYP1A2 1812/4885ESR2 744/4885ESR1 1067/4885 |
| US-20210371398-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS MER INHIBITORS | MERTK, RET, ERBB2 | CYP1A2 1346/4885ESR2 748/4885ESR1 950/4885 |
| US-20130158029-A1 | SIGMA RECEPTOR INHIBITORS | SIGMAR1, TMEM97, OPRL1 | CYP1A2 101/4885ESR2 282/4885ESR1 529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.