SCHEMBL5009580

SCHEMBL5009580

CCN(CC)c1ccc(C(c2ccc(N(CC)CCO)c(C)c2)c2ccc(N(CC)CCO)c(C)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRK6 P43250 1/20 0.41
KMT2A Q03164 4/20 0.40
LMNA P02545 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
TP53 P04637 1/20 0.40
ATM Q13315 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ALDH1A1 P00352 4/20 0.39
TSHR P16473 2/20 0.39
MAPT P10636 4/20 0.38
PSMD14 O00487 2/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
MITF O75030 1/20 0.38
GAA P10253 2/20 0.38
PKM P14618 1/20 0.38
HTT P42858 1/20 0.38
MCL1 Q07820 1/20 0.38
CNR2 P34972 8/20 0.37
S100B P04271 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5013162 0.88 GRK6 (0.47) GRK6KMT2ALMNAATMALDH1A1
SCHEMBL14431219 0.82 GRK6 (0.44) GRK6ATMALDH1A1TSHRMAPT
SCHEMBL10611474 0.80 GRK6 (0.43) GRK6KMT2AATMNPSR1ALDH1A1
SCHEMBL22415867 0.78 SLC2A1 (0.45) GRK6KMT2ALMNASMN1; SMN2TP53
SCHEMBL5009582 0.78 KMT2A (0.49) GRK6KMT2ALMNASMN1; SMN2TP53
SCHEMBL5009578 0.78 MAPT (0.59) GRK6KMT2ALMNASMN1; SMN2TP53
SCHEMBL12342190 0.78 MAPT (0.55) GRK6KMT2ALMNASMN1; SMN2TP53
SCHEMBL20111147 0.76 SLC2A1 (0.46) GRK6KMT2ALMNASMN1; SMN2TP53
SCHEMBL3893912 0.75 KMT2A (0.56) GRK6KMT2ALMNASMN1; SMN2TP53
SCHEMBL131813 0.74 ALDH1A1 (0.56) GRK6KMT2AALDH1A1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080311524-A1 Method For Making Negative-Working Heat-Sensitive Lithographic Printing Plate Precursor AGFA GRAPHICS N.V. (BE) 2008-12-18 US disclosed
EP-1803034-A2 HOLOGRAPHIC STORAGE MEDIUM General Electric Company (US) 2007-07-04 EP disclosed
WO-2006044243-A2 HOLOGRAPHIC STORAGE MEDIUM GENERAL ELECTRIC COMPANY A CORPORATION OF THE STATE OF NEW YORK (US) 2006-04-27 WO disclosed
US-20060078802-A1 Holographic storage medium SABIC INNOVATIVE PLASTICS IP B.V. 2006-04-13 US disclosed
EP-0239868-B1 PHOTOCHROMIC SYSTEM, LAYER PREPARED THEREOF AND ITS USE BASF Aktiengesellschaft (DE) 1989-12-27 EP disclosed
US-4857438-A Photochromic system and layers produced therewith BASF AKTIENGESELLSCHAFT (DE) 1989-08-15 US disclosed
EP-0239868-A1 Photochromic system, layer prepared thereof and its use BASF Aktiengesellschaft (DE) 1987-10-07 EP disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4315068-A CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS RICOH CO., LTD. (JP) 1982-02-09 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4251619-A Process for forming photo-polymeric image KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-02-17 US disclosed