Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 12/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 10/20 | 0.49 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.49 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 2/20 | 0.34 |
| ▸ | MERTK | Q12866 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | NAE1 | Q13564 | 1/20 | 0.33 |
| ▸ | UBA3 | Q8TBC4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5004689 | 0.90 | HSP90AB1 (0.47) | HSP90AA1HSP90AB1OPRM1 | |
| SCHEMBL5008000 | 0.89 | HSP90AB1 (0.49) | HSP90AA1HSP90AB1HSP90B1TRAP1OPRM1 | |
| SCHEMBL5009862 | 0.89 | HSP90AB1 (0.47) | HSP90AA1HSP90AB1OPRM1 | |
| SCHEMBL5001466 | 0.88 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL5004777 | 0.88 | HSP90AB1 (0.49) | HSP90AA1HSP90AB1HSP90B1TRAP1AXL | |
| SCHEMBL5009955 | 0.86 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL5009954 | 0.86 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL24334736 | 0.80 | HSP90AB1 (0.46) | HSP90AA1HSP90AB1HSP90B1TRAP1OPRM1 | |
| SCHEMBL29529767 | 0.80 | HSP90AB1 (0.46) | HSP90AA1HSP90AB1HSP90B1TRAP1OPRM1 | |
| SCHEMBL27196733 | 0.79 | HSP90AB1 (0.61) | HSP90AA1HSP90AB1HSP90B1TRAP1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269193-A1 | Tetrahydroindole and Tetrahydroindazole Derivatives | SERENEX, INC. | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269193-A1 | Tetrahydroindole and Tetrahydroindazole Derivatives | HSF1, HSP90AB1, TPH1 | HSP90AA1 4/4885HSP90AB1 2/4885HSP90B1 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.