Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9483197 | 0.92 | TSHR (0.53) | CNR2CNR1TSHRS1PR1MAPK1 | |
| SCHEMBL5011808 | 0.89 | TSHR (0.54) | CNR2CNR1TSHRS1PR1MAPK1 | |
| SCHEMBL6252652 | 0.89 | TSHR (0.53) | CNR2CNR1TSHRS1PR1MAPK1 | |
| SCHEMBL3190991 | 0.88 | SLC2A1 (0.47) | CNR2CNR1NPC1MAPK1ALDH1A1 | |
| SCHEMBL5011923 | 0.87 | TSHR (0.48) | CNR2CNR1TSHRS1PR1MAPK1 | |
| SCHEMBL11104541 | 0.87 | TSHR (0.51) | CNR2CNR1TSHRS1PR1MAPK1 | |
| SCHEMBL12342188 | 0.85 | MAPT (0.44) | CNR2CNR1NPC1MAPK1ALDH1A1 | |
| SCHEMBL11520299 | 0.85 | CYP2C19 (0.51) | CNR2TSHRS1PR1MAPK1NR1H2 | |
| SCHEMBL10596976 | 0.84 | TSHR (0.44) | CNR2CNR1TSHRS1PR1NPC1 | |
| SCHEMBL5011777 | 0.84 | TSHR (0.56) | CNR2CNR1TSHRS1PR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080311524-A1 | Method For Making Negative-Working Heat-Sensitive Lithographic Printing Plate Precursor | AGFA GRAPHICS N.V. (BE) | 2008-12-18 | — | — | US | disclosed |
| EP-0239868-B1 | PHOTOCHROMIC SYSTEM, LAYER PREPARED THEREOF AND ITS USE | BASF Aktiengesellschaft (DE) | 1989-12-27 | — | — | EP | disclosed |
| US-4857438-A | Photochromic system and layers produced therewith | BASF AKTIENGESELLSCHAFT (DE) | 1989-08-15 | — | — | US | disclosed |
| EP-0239868-A1 | Photochromic system, layer prepared thereof and its use | BASF Aktiengesellschaft (DE) | 1987-10-07 | — | — | EP | disclosed |
| US-4332884-A | USING A DIOXIME CHELATING AGENT | RICOH CO., LTD. (JP) | 1982-06-01 | — | — | US | disclosed |
| US-4306014-A | AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM | RICOH CO., LTD. (JP) | 1981-12-15 | — | — | US | disclosed |
| US-4251619-A | Process for forming photo-polymeric image | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1981-02-17 | — | — | US | disclosed |