Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780437 | 0.97 | CYP2C19 (0.51) | CYP2C19MCL1GAAMAPTPKM | |
| SCHEMBL9483197 | 0.93 | TSHR (0.53) | CYP2C19MCL1GAAMAPTPKM | |
| SCHEMBL11323458 | 0.90 | CYP2C19 (0.45) | CYP2C19MCL1GAAMAPTPKM | |
| SCHEMBL5011808 | 0.90 | TSHR (0.54) | CYP2C19MCL1GAAMAPTPKM | |
| SCHEMBL6252652 | 0.90 | TSHR (0.53) | CYP2C19MCL1GAAMAPTPKM | |
| SCHEMBL10598118 | 0.90 | CYP2C19 (0.42) | CYP2C19MCL1GAAMAPTPKM | |
| SCHEMBL11104541 | 0.88 | TSHR (0.51) | CYP2C19MCL1GAAMAPTPKM | |
| SCHEMBL5011923 | 0.88 | TSHR (0.48) | CYP2C19MCL1GAAMAPTPKM | |
| SCHEMBL10828353 | 0.88 | CRHBP (0.42) | CYP2C19MCL1GAAMAPTPKM | |
| SCHEMBL12680403 | 0.87 | CYP2C19 (0.50) | CYP2C19MCL1GAAMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140529-A | Charge transport overlayer in photoconductive element and method of use | XEROX CORPORATION (US) | 1979-02-20 | — | — | US | claimed |
| US-4140529-A | Charge transport overlayer in photoconductive element and method of use | XEROX CORPORATION (US) | 1979-02-20 | — | — | US | disclosed |