Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.61 |
| ▸ | BRAF | P15056 | 14/20 | 0.56 |
| ▸ | LYN | P07948 | 1/20 | 0.51 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12764355 | 0.89 | BRAF (0.62) | MAPK14BRAF | |
| SCHEMBL13130530 | 0.87 | BRAF (0.60) | MAPK14BRAF | |
| SCHEMBL1936141 | 0.87 | BRAF (0.60) | MAPK14BRAF | |
| SCHEMBL13797991 | 0.86 | MAPK14 (0.67) | MAPK14BRAFLYNMAPK9 | |
| SCHEMBL10104561 | 0.86 | BRAF (0.59) | MAPK14BRAF | |
| SCHEMBL1934598 | 0.85 | MAPK14 (0.58) | MAPK14BRAFLYNMAPK9 | |
| SCHEMBL13130531 | 0.85 | BRAF (0.58) | MAPK14BRAF | |
| SCHEMBL2670966 | 0.84 | MAPK14 (0.57) | MAPK14BRAFLYNMAPK9MEN1 | |
| SCHEMBL13797933 | 0.84 | MAPK14 (0.68) | MAPK14BRAFLYNMAPK9MEN1 | |
| SCHEMBL5163836 | 0.84 | BRAF (0.62) | MAPK14BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1887003-A1 | 3-[4-HETEROCYCLYL -1,2,3-TRIAZOL-1-YL]-N-ARYL-BENZAMIDES AS INHIBITORS OF THE CYTOKINES PRODUCTION FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES | Boehringer Ingelheim Pharmaceuticals, Inc. (US) | 2008-02-13 | — | — | EP | disclosed |