Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | DAO | P14920 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | CTRC | Q99895 | 3/20 | 0.30 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.30 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.30 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29074297 | 0.74 | CALM1 (0.42) | CALM1ADH1BADH1CADH1AADH7 | |
| SCHEMBL27650349 | 0.74 | — | — | |
| SCHEMBL7385803 | 0.73 | CALM1 (0.41) | CALM1ALDH1A1LMNA | |
| SCHEMBL2547836 | 0.72 | POLB (0.40) | CALM1MGLLALDH1A1LMNAPLA2G10 | |
| SCHEMBL27283619 | 0.72 | — | — | |
| SCHEMBL27687617 | 0.72 | — | — | |
| SCHEMBL17512439 | 0.71 | CALM1 (0.39) | CALM1MMP9DAO | |
| SCHEMBL442708 | 0.70 | PLA2G10 (0.42) | CALM1ALDH1A1LMNANPSR1PLA2G10 | |
| SCHEMBL3034022 | 0.68 | CALM1 (0.35) | CALM1MMP9 | |
| SCHEMBL27670481 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537517-B1 | Method for the preparation of 2,2-difluorobenzo(1,3)dioxolecarbaldehydes and intermediates | BAYER AG (DE) | 1997-01-22 | — | — | EP | claimed |
| US-5420308-A | 2,2-difluorobenzo (1,3)-dioxole-carbaldehydes and new intermediate products | BAYER AKTIENGESELLSCHAFT (DE) | 1995-05-30 | — | — | US | claimed |
| US-7351735-B2 | Benzofuran and benzothiophene derivatives useful in the treatment of hyper-proliferative disorders | BAYER PHARMACEUTICALS CORPORATION (US) | 2008-04-01 | — | — | US | disclosed |
| US-20050139814-A1 | Benzofuran and benzothiophene derivatives useful in the treatmint of hyper-proliferative disorders | BAYER HEALTHCARE LLC | 2005-06-30 | — | — | US | disclosed |
| EP-0537517-B1 | Method for the preparation of 2,2-difluorobenzo(1,3)dioxolecarbaldehydes and intermediates | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |
| US-5525739-A | Process for the preparation of 2,2-difluorobenzo[1,3]-dioxole-carbaldehydes and new intermediate products | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-11 | — | — | US | disclosed |
| US-5525739-A | Process for the preparation of 2,2-difluorobenzo[1,3]-dioxole-carbaldehydes and new intermediate products | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-11 | — | — | US | disclosed |
| US-5420308-A | 2,2-difluorobenzo (1,3)-dioxole-carbaldehydes and new intermediate products | BAYER AKTIENGESELLSCHAFT (DE) | 1995-05-30 | — | — | US | disclosed |
| US-5420308-A | 2,2-difluorobenzo (1,3)-dioxole-carbaldehydes and new intermediate products | BAYER AKTIENGESELLSCHAFT (DE) | 1995-05-30 | — | — | US | disclosed |
| EP-0537517-A1 | Method for the preparation of 2,2-difluorobenzo(1,3)dioxolecarbaldehydes and intermediates | BAYER AG (DE) | 1993-04-21 | — | — | EP | disclosed |
| EP-0537517-A1 | Method for the preparation of 2,2-difluorobenzo(1,3)dioxolecarbaldehydes and intermediates | BAYER AG (DE) | 1993-04-21 | — | — | EP | disclosed |