Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15526785 | 0.85 | MAPT (0.57) | TDP1MAPTCA1CA2MEN1 | |
| SCHEMBL6419787 | 0.82 | MAPT (0.60) | TDP1MAPTCA1CA2CA12 | |
| SCHEMBL13994623 | 0.80 | POLB (0.56) | TDP1MAPTCA1CA12CA9 | |
| SCHEMBL5011867 | 0.78 | NPC1 (0.53) | TDP1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL2246931 | 0.77 | CA1 (0.50) | TDP1MAPTCA1CA2CA12 | |
| SCHEMBL600655 | 0.76 | MAPT (0.58) | TDP1MAPTCA1CA2CA12 | |
| SCHEMBL14369281 | 0.76 | MAPT (0.58) | TDP1MAPTCA1CA2CA12 | |
| SCHEMBL13753393 | 0.76 | MAPT (0.62) | TDP1MAPTCA1CA2CA12 | |
| SCHEMBL5561230 | 0.74 | MAPT (0.60) | TDP1MAPTCA1CA2CA12 | |
| SCHEMBL23600 | 0.74 | CA1 (0.80) | TDP1MAPTCA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080319055-A1 | Cooling Compounds | GIVAUDAN SA (CH) | 2008-12-25 | — | — | US | disclosed |
| US-20080319055-A1 | Cooling Compounds | GIVAUDAN SA (CH) | 2008-12-25 | — | — | US | disclosed |
| US-20080319055-A1 | Cooling Compounds | GIVAUDAN SA (CH) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319055-A1 | Cooling Compounds | TAS2R1, TAS2R43, TAS2R3 | TDP1 2571/4885MAPT 2788/4885CA1 717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.