Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13994623 | 0.90 | POLB (0.56) | NPC1RAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL6416083 | 0.82 | NPC1 (0.60) | NPC1RAB9ACTDSP1SMN1; SMN2GAA | |
| SCHEMBL14714456 | 0.79 | NPC1 (0.56) | NPC1RAB9ACTDSP1SMN1; SMN2GAA | |
| SCHEMBL5010345 | 0.78 | TDP1 (0.53) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL15526785 | 0.77 | MAPT (0.57) | NPC1RAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL3135725 | 0.75 | NPC1 (0.60) | NPC1RAB9ACTDSP1SMN1; SMN2MAPT | |
| SCHEMBL24571837 | 0.75 | POLB (0.56) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL4067128 | 0.75 | ALDH1A1 (0.71) | NPC1RAB9ACTDSP1SMN1; SMN2GAA | |
| SCHEMBL5004806 | 0.75 | NPC1 (0.55) | NPC1RAB9ACTDSP1SMN1; SMN2GAA | |
| SCHEMBL28536704 | 0.73 | CTDSP1 (0.53) | NPC1RAB9ACTDSP1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080319055-A1 | Cooling Compounds | GIVAUDAN SA (CH) | 2008-12-25 | — | — | US | disclosed |
| US-20080319055-A1 | Cooling Compounds | GIVAUDAN SA (CH) | 2008-12-25 | — | — | US | disclosed |
| US-20080319055-A1 | Cooling Compounds | GIVAUDAN SA (CH) | 2008-12-25 | — | — | US | disclosed |
| EP-1860960-A1 | COOLING COMPOUNDS | Givaudan SA (CH) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006099762-A1 | COOLING COMPOUNDS | GIVAUDAN SA (CH) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319055-A1 | Cooling Compounds | TAS2R1, TAS2R43, TAS2R3 | NPC1 1037/4885RAB9A 3133/4885CTDSP1 676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.