Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.59 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13109869 | 0.83 | NPC1 (0.60) | TAS1R3TAS1R1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1740558 | 0.82 | NPC1 (0.59) | TAS1R3TAS1R1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL12024481 | 0.82 | TAS1R3 (0.59) | TAS1R3TAS1R1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10192179 | 0.81 | TAS1R3 (0.58) | TAS1R3TAS1R1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17822216 | 0.80 | TAS1R3 (0.57) | TAS1R3TAS1R1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13702266 | 0.80 | HPGD (0.66) | TAS1R3TAS1R1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10192182 | 0.78 | TAS1R3 (0.55) | TAS1R3TAS1R1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5011642 | 0.78 | TAS1R3 (0.61) | TAS1R3TAS1R1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5192592 | 0.78 | KMT2A (0.70) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL31019604 | 0.78 | NPC1 (0.66) | TAS1R3TAS1R1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080319055-A1 | Cooling Compounds | GIVAUDAN SA (CH) | 2008-12-25 | — | — | US | disclosed |
| US-20080319055-A1 | Cooling Compounds | GIVAUDAN SA (CH) | 2008-12-25 | — | — | US | disclosed |
| US-20080319055-A1 | Cooling Compounds | GIVAUDAN SA (CH) | 2008-12-25 | — | — | US | disclosed |
| EP-1860960-A1 | COOLING COMPOUNDS | Givaudan SA (CH) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006099762-A1 | COOLING COMPOUNDS | GIVAUDAN SA (CH) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319055-A1 | Cooling Compounds | TAS2R1, TAS2R43, TAS2R3 | TAS1R3 22/4885TAS1R1 23/4885RAB9A 3133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.