Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 5/20 | 0.54 |
| ▸ | BCHE | P06276 | 4/20 | 0.54 |
| ▸ | BACE1 | P56817 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | LSS | P48449 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5542857 | 0.92 | ALDH1A1 (0.64) | ALDH1A1TSHRACHEBCHEBACE1 | |
| SCHEMBL15591085 | 0.78 | ALDH1A1 (0.68) | ALDH1A1TSHRACHEBCHEBACE1 | |
| SCHEMBL2856132 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TSHRACHEBCHEBACE1 | |
| SCHEMBL13478353 | 0.76 | ALDH1A1 (0.61) | ALDH1A1TSHRACHEBCHEBACE1 | |
| SCHEMBL17033950 | 0.76 | TSHR (0.69) | ALDH1A1TSHRACHEBCHEBACE1 | |
| SCHEMBL14699678 | 0.76 | ALDH1A1 (0.65) | ALDH1A1TSHRACHEBCHEBACE1 | |
| SCHEMBL24780094 | 0.75 | BCHE (0.67) | ALDH1A1TSHRACHEBCHEBACE1 | |
| SCHEMBL24478089 | 0.74 | ALDH1A1 (0.71) | ALDH1A1TSHRACHEBCHEBACE1 | |
| SCHEMBL8792056 | 0.74 | TSHR (0.55) | ALDH1A1TSHRACHEBCHEBACE1 | |
| SCHEMBL12625981 | 0.74 | ALDH1A1 (0.66) | ALDH1A1TSHRACHEBCHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673083-A4 | N-SUBSTITUTED AZACYCLES | BAYER CROPSCIENCE AG (DE) | 2008-12-17 | — | — | EP | disclosed |
| EP-1673083-A2 | N-SUBSTITUTED AZACYCLES | FMC CORPORATION (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005036961-A2 | N-SUBSTITUTED AZACYCLES | FMC CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |