Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 6/20 | 0.55 |
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19107617 | 0.91 | MAPT (0.58) | MAPTGLANPSR1HTR1AHTR7 | |
| SCHEMBL2114983 | 0.85 | HTR1A (0.73) | MAPTHTR1AHTR7DRD2 | |
| SCHEMBL5010735 | 0.84 | KMT2A (0.58) | MAPTHTR1AHTR7MEN1KMT2A | |
| SCHEMBL5009446 | 0.84 | HTR1A (0.72) | MAPTNPSR1HTR1AHTR7KMT2A | |
| SCHEMBL15650606 | 0.84 | GFER (0.56) | MAPTHTR1AHTR7MEN1KMT2A | |
| SCHEMBL2114078 | 0.84 | HTR1A (0.72) | HTR1AHTR7DRD2DRD4DRD3 | |
| SCHEMBL26373091 | 0.83 | S1PR1 (0.61) | MAPTGLANPSR1CA1CA2 | |
| Hydrochloric Acid SCHEMBL9811592 | 0.83 | HTR1A (0.71) | MAPTHTR1AHTR7DRD2 | |
| SCHEMBL12041659 | 0.83 | HTR1A (0.51) | MAPTHTR1AHTR7MEN1KMT2A | |
| SCHEMBL5011458 | 0.83 | KMT2A (0.75) | HTR1ACA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093920-A2 | 1,2-DIHYDRO-1-OXOPHTHALAZINYL DERIVATIVES HAVING BIOLOGICAL ACTIVITY ON SEROTONIN RECEPTORS 5-HT2A AND 5-HT2C, AND PREPARATION THEREOF | DONGBU HITEK CO., LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |