SCHEMBL5010754

SCHEMBL5010754

C=C(C)C(=O)OC(C)SC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29134966 0.85 TSHR (0.37) TSHRALDH1A1
SCHEMBL491118 0.79 TSHR (0.45) TSHRALDH1A1
SCHEMBL3081441 0.77 TSHR (0.43) TSHRALDH1A1
SCHEMBL8944639 0.77 TSHR (0.43) TSHRALDH1A1
SCHEMBL2430676 0.77 TSHR (0.43) TSHRALDH1A1
SCHEMBL2429804 0.75 TSHR (0.42) TSHRALDH1A1
SCHEMBL27800273 0.75 TSHR (0.42) TSHRALDH1A1
SCHEMBL28432487 0.75 TSHR (0.42) TSHRALDH1A1
SCHEMBL372920 0.74 ALDH1A1 (0.44) TSHRALDH1A1
SCHEMBL23494390 0.73 TSHR (0.41) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1776399-B1 MONODISPERSE POLYMERS CONTAINING (ALKYL)ACRYLIC ACID MOIETIES, PRECURSORS AND METHODS FOR MAKING THEM AND THEIR APPLICATIONS UNIV GENT (BE) 2012-11-14 EP claimed
EP-3018151-A1 PROCESS FOR PREPARING INERT RAFT POLYMERS Universiteit Gent (BE) 2016-05-11 EP disclosed
US-20130096268-A1 MONODISPERSE POLYMERS CONTAINING (ALKYL)ACRYLIC ACID MOIETIES, PRECURSORS AND METHODS FOR MAKING THEM AND THEIR APPLICATIONS UNIVERSITEIT GENT (BE) 2013-04-18 US disclosed
US-20080262160-A1 Monodisperse Polymers Containing (Alkyl)Acrylic Acid Moieties, Precursors and Methods for Making them and their Applications UNIVERSITEIT GENT (BE) 2008-10-23 US disclosed