Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5011393 | 0.88 | PRKCE (0.43) | FFAR4DPP4CTSKCYP3A4HSD11B1 | |
| SCHEMBL4508572 | 0.84 | FFAR4 (0.42) | FFAR4CTSKCYP3A4APPCYP2C19 | |
| SCHEMBL4491283 | 0.82 | FFAR4 (0.45) | FFAR4CYP3A4APPCYP2C19CYP2C9 | |
| SCHEMBL4514618 | 0.81 | CYP3A4 (0.40) | CTSKCYP3A4HSD11B1APPCYP2C19 | |
| SCHEMBL4514062 | 0.80 | FFAR4 (0.48) | FFAR4CYP3A4APPCYP2C19CYP2C9 | |
| SCHEMBL4503949 | 0.79 | OPRM1 (0.47) | FFAR4CYP3A4APPCYP2C19CYP2C9 | |
| SCHEMBL4512900 | 0.79 | CYP2C19 (0.40) | FFAR4CTSKCYP3A4HSD11B1APP | |
| SCHEMBL4497508 | 0.79 | FFAR4 (0.41) | FFAR4CTSKCYP3A4HSD11B1APP | |
| SCHEMBL5013478 | 0.77 | APP (0.42) | FFAR4CTSKCYP3A4APPCYP2C19 | |
| SCHEMBL4506497 | 0.77 | FFAR4 (0.44) | FFAR4CTSKCYP3A4HSD11B1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893562-A1 | REVERSIBLE INHIBITORS OF MONOAMINE OXIDASE A AND B | Merck Frosst Canada Ltd. (CA) | 2008-03-05 | — | — | EP | claimed |
| WO-2006133559-A1 | REVERSIBLE INHIBITORS OF MONOAMINE OXIDASE A AND B | MERCK FROSST CANADA LTD. (CA) | 2006-12-21 | — | — | WO | claimed |