SCHEMBL5011555

SCHEMBL5011555

Nc1c(C(=O)O)cc([N+](=O)[O-])c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.65
MAPK1 P28482 4/20 0.65
MEN1 O00255 2/20 0.65
THRB P10828 2/20 0.65
KMT2A Q03164 2/20 0.65
KDM4E B2RXH2 2/20 0.65
USP2 O75604 1/20 0.65
PKM P14618 1/20 0.65
MCL1 Q07820 1/20 0.65
NPSR1 Q6W5P4 1/20 0.65
ALDH1A1 P00352 4/20 0.55
POLB P06746 2/20 0.55
LMNA P02545 2/20 0.55
RECQL P46063 1/20 0.55
APEX1 P27695 1/20 0.51
CASP6 P55212 1/20 0.51
GRK6 P43250 1/20 0.50
P2RY12 Q9H244 3/20 0.47
P2RY4 P51582 4/20 0.46
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31361445 1.00 MAPT (0.65) MAPTMAPK1MEN1THRBKMT2A
Hydrochloric Acid SCHEMBL10886949 0.99 MAPT (0.63) MAPTMAPK1MEN1THRBKMT2A
SCHEMBL9816533 0.89 GRK6 (0.65) MAPTMAPK1MEN1THRBKMT2A
SCHEMBL10392723 0.88 MAPT (0.50) MAPTMAPK1MEN1THRBKMT2A
SCHEMBL10885230 0.85 MAPT (0.47) MAPTMAPK1MEN1THRBKMT2A
SCHEMBL11628597 0.83 MAPT (0.51) MAPTMAPK1MEN1THRBKMT2A
SCHEMBL11212007 0.82 MAPT (0.55) MAPTMAPK1MEN1THRBKMT2A
SCHEMBL11818043 0.81 MAPT (0.54) MAPTMAPK1MEN1THRBKMT2A
SCHEMBL11794690 0.80 SMN1; SMN2 (0.45) MAPTMAPK1MEN1THRBKMT2A
SCHEMBL3375833 0.80 MAPT (0.48) MAPTMAPK1MEN1THRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114105791-A Novel synthesis method of 1, 4-diaminoanthraquinone-2-carboxylic acid decahydro-2-naphthyl ester 烟台丰鲁精细化工有限责任公司 2022-03-01 CN claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
JP-62138291-A None JP disclosed
JP-58042684-A None JP disclosed
JP-1178495-A None JP disclosed
CN-119179211-A Microcapsule polymerization coated dye liquid crystal nanometer light valve and preparation method thereof 中禾科技(常州)股份有限公司 2024-12-24 CN disclosed
CN-118530188-A Modifier condensate and preparation method and application thereof, and method for preparing modified polymer 中国石油化工股份有限公司 2024-08-23 CN disclosed
CN-114105791-A Novel synthesis method of 1, 4-diaminoanthraquinone-2-carboxylic acid decahydro-2-naphthyl ester 烟台丰鲁精细化工有限责任公司 2022-03-01 CN disclosed
CN-114105791-A Novel synthesis method of 1, 4-diaminoanthraquinone-2-carboxylic acid decahydro-2-naphthyl ester 烟台丰鲁精细化工有限责任公司 2022-03-01 CN disclosed
CN-101374809-A Anthraquinone derivatives as markers for liquids BASF SE (DE) 2009-02-25 CN disclosed
US-20080318331-A1 Anthraquinone Derivatives as Markers For Liquids BASF SE (DE) 2008-12-25 US disclosed
US-4284411-A CONDENSATION, PIGMENTING BAYER AKTIENGESELLSCHAFT (DE) 1981-08-18 US disclosed
EP-0027213-A1 Process for the production of cellulose by using dispersions of nitroanthraquinones BAYER AG (DE) 1981-04-22 EP disclosed
US-4260540-A SPIN DYEING POLYACRYLONITRILE BAYER AKTIENGESELLSCHAFT (DE) 1981-04-07 US disclosed
US-4246401-A Axomethine pigments BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 US disclosed
EP-0021264-A1 Process for the delignification of lignocellulosic materials BAYER AG (DE) 1981-01-07 EP disclosed
US-4225489-A Heterocyclic azo dyes and pigments containing 4-quinazolinone moieties BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
US-4046785-A Process for preparing aminoanthraquinones MITSUI TOATSU CHEMICALS, INC. (JA) 1977-09-06 US disclosed
US-3886188-A Production of pure 1-amino-4-nitroanthraquinone-2-carboxylic acid BASF AG 1975-05-27 US disclosed
US-3886188-A Production of pure 1-amino-4-nitroanthraquinone-2-carboxylic acid BASF AG 1975-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080318331-A1 Anthraquinone Derivatives as Markers For Liquids ANTXR2, AQP1, MYADM MAPT 4644/4885MAPK1 2287/4885MEN1 1595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.