SCHEMBL5011707

SCHEMBL5011707

CCCCCCOc1ccc(C(c2ccc(N(C)C)cc2)c2ccc(N(C)C)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 2/20 0.56
PTGES O14684 1/20 0.54
NR5A1 Q13285 1/20 0.51
HDAC1 Q13547 1/20 0.50
GAA P10253 1/20 0.49
LMNA P02545 1/20 0.47
MMP9 P14780 1/20 0.47
MMP8 P22894 1/20 0.47
MMP13 P45452 1/20 0.47
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46
LTA4H P09960 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
THRA P10827 1/20 0.46
THRB P10828 1/20 0.46
PLA2G4B P0C869 1/20 0.45
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23302979 0.90 PTGES (0.62) PTGESNR5A1HDAC1GAALMNA
SCHEMBL11000930 0.90 PTGES (0.62) PTGESNR5A1HDAC1GAALMNA
SCHEMBL12589626 0.90 PTGES (0.62) PTGESNR5A1HDAC1GAALMNA
SCHEMBL11001964 0.90 PTGES (0.62) PTGESNR5A1HDAC1GAALMNA
SCHEMBL1263398 0.90 PTGES (0.62) PTGESNR5A1HDAC1GAALMNA
SCHEMBL18102770 0.89 SLC2A1 (0.61) SLC2A1PTGESHDAC1GAATSHR
Hydrochloric Acid SCHEMBL23302958 0.89 PTGES (0.60) SLC2A1PTGESNR5A1HDAC1GAA
SCHEMBL13172437 0.88 NR5A1 (0.63) SLC2A1NR5A1GAALMNAMMP9
SCHEMBL18104334 0.86 NR5A1 (0.50) SLC2A1NR5A1LMNAMMP9MMP8
SCHEMBL1263730 0.85 PTGES (0.68) PTGESNR5A1HDAC1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080311524-A1 Method For Making Negative-Working Heat-Sensitive Lithographic Printing Plate Precursor AGFA GRAPHICS N.V. (BE) 2008-12-18 US disclosed
US-20060078802-A1 Holographic storage medium SABIC INNOVATIVE PLASTICS IP B.V. 2006-04-13 US disclosed
EP-0239868-B1 PHOTOCHROMIC SYSTEM, LAYER PREPARED THEREOF AND ITS USE BASF Aktiengesellschaft (DE) 1989-12-27 EP disclosed
US-4857438-A Photochromic system and layers produced therewith BASF AKTIENGESELLSCHAFT (DE) 1989-08-15 US disclosed
EP-0239868-A1 Photochromic system, layer prepared thereof and its use BASF Aktiengesellschaft (DE) 1987-10-07 EP disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4251619-A Process for forming photo-polymeric image KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-02-17 US disclosed