SCHEMBL5011845

SCHEMBL5011845

CCN(CC)c1ccc(C(c2ccc(NCCCc3ccccc3)cc2)c2ccc(NCCCc3ccccc3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 6/20 0.49
NOX1 Q9Y5S8 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
KCNH2 Q12809 2/20 0.42
CHRM2 P08172 1/20 0.42
HTR1A P08908 1/20 0.42
ADRA2A P08913 1/20 0.42
CHRM1 P11229 1/20 0.42
DRD1 P21728 1/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
ADRA1A P35348 1/20 0.42
OPRM1 P35372 1/20 0.42
DRD3 P35462 1/20 0.42
SLC6A3 Q01959 1/20 0.42
NPY1R P25929 1/20 0.41
NPY2R P49146 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5010082 0.86 NPC1 (0.51) CNR2NPC1RAB9AMEN1KMT2A
SCHEMBL5011819 0.86 CNR2 (0.45) CNR2NOX1NPC1RAB9AMEN1
SCHEMBL5011812 0.86 CNR2 (0.42) CNR2NOX1NPC1RAB9AMEN1
SCHEMBL3905892 0.84 L3MBTL1 (0.52) CNR2MEN1KMT2AKCNH2DRD3
SCHEMBL5011785 0.79 PIK3CD (0.40) CNR2NOX1NPC1RAB9AMEN1
SCHEMBL5011778 0.79 HTT (0.40) CNR2NOX1NPC1RAB9AMEN1
SCHEMBL5010087 0.79 CNR1 (0.53) CNR2NPC1RAB9AMEN1KMT2A
SCHEMBL3894772 0.78 GAA (0.41) CNR2NOX1NPC1RAB9AMEN1
SCHEMBL6340962 0.77 CNR2 (0.49) CNR2NOX1NPC1RAB9AMEN1
SCHEMBL109699 0.76 CNR2 (0.53) CNR2NOX1NPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080311524-A1 Method For Making Negative-Working Heat-Sensitive Lithographic Printing Plate Precursor AGFA GRAPHICS N.V. (BE) 2008-12-18 US disclosed
US-20060078802-A1 Holographic storage medium SABIC INNOVATIVE PLASTICS IP B.V. 2006-04-13 US disclosed
EP-0239868-B1 PHOTOCHROMIC SYSTEM, LAYER PREPARED THEREOF AND ITS USE BASF Aktiengesellschaft (DE) 1989-12-27 EP disclosed
US-4857438-A Photochromic system and layers produced therewith BASF AKTIENGESELLSCHAFT (DE) 1989-08-15 US disclosed
EP-0239868-A1 Photochromic system, layer prepared thereof and its use BASF Aktiengesellschaft (DE) 1987-10-07 EP disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4251619-A Process for forming photo-polymeric image KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-02-17 US disclosed