Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 4/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | GRB2 | P62993 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29142089 | 0.95 | AKR1B1 (0.41) | AKR1B1THRBMCL1MEN1POLB | |
| SCHEMBL28816931 | 0.84 | AKR1B1 (0.47) | AKR1B1THRBMCL1MEN1POLB | |
| SCHEMBL21352167 | 0.84 | AKR1B1 (0.41) | AKR1B1THRBTHRA | |
| SCHEMBL3366555 | 0.84 | CXCL8 (0.40) | AKR1B1THRBMEN1POLBKMT2A | |
| SCHEMBL30835160 | 0.84 | CXCL8 (0.40) | AKR1B1THRBMEN1POLBKMT2A | |
| SCHEMBL10479066 | 0.80 | PTGDR2 (0.42) | AKR1B1MEN1KMT2AHSD17B10SRC | |
| SCHEMBL29661155 | 0.80 | PTGDR2 (0.46) | AKR1B1THRBMEN1KMT2ATDP1 | |
| SCHEMBL29710650 | 0.80 | PTGDR2 (0.42) | AKR1B1MEN1KMT2AHSD17B10SRC | |
| SCHEMBL1758414 | 0.80 | PTGDR2 (0.46) | AKR1B1THRBMEN1KMT2ATDP1 | |
| SCHEMBL1097092 | 0.80 | AKR1B1 (0.42) | AKR1B1THRBMCL1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9461249-B2 | Compounds for organic electronic devices | MERCK PATENT GMBH (DE) | 2016-10-04 | — | — | US | disclosed |
| US-20150031896-A1 | COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-01-29 | — | — | US | disclosed |
| US-8852756-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-10-07 | — | — | US | disclosed |
| US-8334058-B2 | Emitters for systems which emit in dark blue; stable, significantly longer lifetime; can be sublimed well without decomposition; easier to process; more suitable for OLEDs; operating voltage, power efficiency remain unchanged at large layer thicknesses; important for production of full-colour displays | MERCK PATENT GMBH (DE) | 2012-12-18 | — | — | US | disclosed |
| US-20080220285-A1 | Derivatives of fused aromatic systems; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers; high efficiency and high stability on use in organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2008-09-11 | — | — | US | disclosed |
| US-20080145708-A1 | Compounds For Organic Electronic Devices | MERCK PATENT GMBH (DE) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080220285-A1 | Derivatives of fused aromatic systems; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers; high efficiency and high stability on use in organic electroluminescent devices | TYR, DDT, PAH | AKR1B1 570/4885THRB 3335/4885MCL1 1583/4885 |
| US-20150031896-A1 | COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | TYR, TOE1, GPX1 | AKR1B1 3180/4885THRB 3726/4885MCL1 2676/4885 |
| US-20080145708-A1 | Compounds For Organic Electronic Devices | TYR, TOE1, GPX1 | AKR1B1 3180/4885THRB 3726/4885MCL1 2676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.