SCHEMBL5012376

SCHEMBL5012376

Cc1cc(C(C)(C)c2ccc(OCC(O)CO)c(C)c2)ccc1OCC(O)CO

nearest known ligand 0.69

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
VDR P11473 11/20 0.69
AR P10275 11/20 0.69
KDM4E B2RXH2 1/20 0.59
CYP1A2 P05177 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30816403 0.93 AR (0.67) VDRARKDM4ECYP1A2
SCHEMBL30816341 0.93 AR (0.67) VDRARKDM4ECYP1A2
SCHEMBL30816371 0.93 AR (0.67) VDRARKDM4ECYP1A2
SCHEMBL12573978 0.93 AR (0.62) VDRARKDM4ECYP1A2
SCHEMBL19459687 0.93 AR (0.67) VDRARKDM4ECYP1A2
SCHEMBL19483474 0.93 AR (0.67) VDRARKDM4ECYP1A2
SCHEMBL19459648 0.93 AR (0.67) VDRARKDM4ECYP1A2
SCHEMBL30816338 0.93 AR (0.67) VDRARKDM4ECYP1A2
SCHEMBL19459816 0.93 AR (0.67) VDRARKDM4ECYP1A2
SCHEMBL19460228 0.93 AR (0.67) VDRARKDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8669030-B2 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY, LIMITED (JP) 2014-03-11 US disclosed
US-8669030-B2 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY, LIMITED (JP) 2014-03-11 US disclosed
US-20090131620-A1 POLYIMIDE HAVING AN ALCOHOLIC HYDROXYL GROUP AND A PROCESS FOR THE PREPARATION THEREOF SUGO MICHIHIRO 2009-05-21 US disclosed
US-20090131620-A1 POLYIMIDE HAVING AN ALCOHOLIC HYDROXYL GROUP AND A PROCESS FOR THE PREPARATION THEREOF SUGO MICHIHIRO 2009-05-21 US disclosed
US-20080138725-A1 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY LIMITED (JP) 2008-06-12 US disclosed
US-20080138725-A1 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY LIMITED (JP) 2008-06-12 US disclosed