Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2308301 | 1.00 | KDM4E (0.33) | KDM4EHTTPKMALDH1A1MEN1 | |
| SCHEMBL2307090 | 1.00 | KDM4E (0.33) | KDM4EHTTPKMALDH1A1MEN1 | |
| SCHEMBL2506037 | 0.90 | KDM4E (0.33) | KDM4EHTTPKMALDH1A1MEN1 | |
| SCHEMBL2312254 | 0.90 | KDM4E (0.33) | KDM4EHTTPKMALDH1A1MEN1 | |
| SCHEMBL3344886 | 0.86 | ALDH1A1 (0.31) | KDM4EHTTPKMALDH1A1MEN1 | |
| SCHEMBL17354049 | 0.84 | KDM4E (0.36) | KDM4EHTTPKMALDH1A1MEN1 | |
| SCHEMBL3068264 | 0.84 | ALDH1A1 (0.35) | KDM4EHTTALDH1A1MEN1KMT2A | |
| SCHEMBL5054243 | 0.83 | ALDH1A1 (0.33) | KDM4EHTTPKMALDH1A1MEN1 | |
| SCHEMBL5015624 | 0.82 | ALDH1A1 (0.32) | KDM4EHTTALDH1A1MEN1KMT2A | |
| SCHEMBL2305796 | 0.82 | ALDH1A1 (0.33) | KDM4EHTTPKMALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888597-A2 | ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006120563-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2006-11-16 | — | — | WO | disclosed |